Last year's winner Smad Place will head a field of 20 in the Hennessy Gold Cup at Newbury on Saturday.
Alan King's grey spread-eagled the opposition 12 months ago but will find life tougher with 11lb more on his back.
Beaten favourite that day was Saphir Du Rheu, who returned to something like his best when third at Ascot and will carry 10lb less than when fifth last year.
His trainer Paul Nicholls will also run Scottish National winner Vicente.
Colin Tizzard has carried all before him this season and has two strong chances with Native River, a Grade One winner as a novice, and Theatre Guide, second and third in the race in the past.
Un Temps Pour Tout and Holywell fought out a finish at the Cheltenham Festival and both line up again.
Blaklion won the RSA for Nigel Twiston-Davies in March but was a little disappointing on his return in the Charlie Hall at Wetherby. Stablemate Double Ross also runs.
Henri Parry Morgan has been well backed this week for Peter Bowen, while Aubusson runs for Nick Williams, who won the race in 2010 with Diamond Harry.
Nicky Henderson runs 2013 winner Triolo D'Alene and Vyta Du Roc, with former Seven Barrows assistants Charlie Longsdon and Ben Pauling represented by Coologue and Local Show respectively.
Among those not declared were Virak, Bishops Road, Outlander and Drumacoo.
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Source: At The Races