Bobby Roode is one of the best heels in the business; a man that can really get under his opponent's skin. We all remember his feud with Roderick Strong in NXT. How can we not considering just how gloriously conniving and evil Roode really was!? I think he can be a wonderful antagonist for a white meat babyface like Reigns.
Unfortunately, Roode has been a babyface ever since he moved up to the main roster. Wrestling experts have attributed this to the fact that he has a catchy theme song, one that fans cannot stop singing even if they consciously tried to. Therefore, Roode has never had the opportunity to mix it up with one Roman Reigns, thus far.
At the same time, I can imagine Roode and Reigns mixing it up down the line. There are only so many matches you can do on RAW, despite the stacked roster.