Although the hosts started the series brightly, the English fought back nicely in the subsequent two Tests to gain an unassailable lead in the series.
South Africa will be affected by Kagiso Rabada getting a suspension in the last Test.
Jos Buttler has averaged under 25 with the bat since the Ashes.
Joe Root has scored 200 runs so far and will be looking to close out the series with a valuable contribution with the ball as well.
Last 5 Head To Head
Venue Details and Pitch Report
24 Jan, 01:30 PM IST
New Wanderers Stadium, Johannesburg
Rodney Tucker, Joel Wilson
Bounce and pace are expected but can be unpredictable as the Test match goes on.
Thunderstorms are forecast for the first three days. Possibility of rain.
South Africa will be looking for a series-leveling victory after being thrashed in the third Test. Faf du Plessis, Quinton De Kock, Dean Elgar, and Temba Bavuma will have to bat out of their skins to gift a victory to retiring bowler Vernon Philander. England, on the other hand, will be looking to continue their winning streak and close the series 3-1.