A stunning Manchester Derby as Pep Guardiola outfoxed Jose Mourinho in the first half, with De Bruyne and Iheanacho opening the scoring for the Citizens as they dominated the opening 40 minutes.
Claudio Bravo allowed united a route back into the game with Zlatan Ibrahimovic pulling one back for United.
United started the second half with a bang with Rashford and Herrera making a great impact. The Red Devils did have the ball in the net, but saw it correctly ruled out.
City saw off 5 minutes of injury time, with Claudio Bravo having more nervous moments, but the game ended with Guardiola's side holding out for a pivotal win.
The result leaves Manchester City at the top of the table with 4 wins in 4 games.
90+5' Stones with superb clearance as Bravo nearly makes another mistake.
90+4' United have a free-kick in City's half. Rooney's delivery is cleared by Stones, with City hacking the second ball in away from goal as well. Fernandinho goes into the book.
90+4' Rooney's delivery is palmed away by Bravo, and he earns a soft foul.
90+3' ALMOST! Ibrahimovic's shot looks destined for the bottom corner, but deflects for a corner.
90+2' Oh dear. Zlatan with a wild volley from a Fellaini chest down as United launch the ball into the box repeatedly. Desperate stuff from the Red Devils.
90' 5 added minutes of injury time - The camera pans to Fergie.
90' Zabaleta comes on for De Bruyne, as Pep Guardiola wastes time by initially naming Nolito to come off.
89' Manchester City take a quick free-kick with United asleep, and De Bruyne's charge up the pitch ends with a wild shot on goal.
88' AMAZING DEFENDING! Fernando with a stunning block after Zlatan had headed the ball down to an onrushing Rooney in the box. All hands on deck for City.
87' John Stones with a hack clear. 50 million pounds, people.
85' GREAT DEFENDING! Fernandinho nutmegs Blind as he charges through the middle, but Bailly bails his teammate out just as the City man is about to pull the trigger.
84' Nicolas Otamendi gets treatment for a head injury as there is a break in play.
83' Wayne Rooney goes into the book for a foul on Claudio Bravo, who had dallied on the ball. The Chilean has had a horrible debut so far, no question about it.
82' Pep Guardiola makes some wild gesticulations on the touchline as his team adjusts to Manchester United's crazy new formation.
81' Luke Shaw comes off for Anthony Martial. Jose Mourinho going all attack now!
80' City appeal for a penalty as Nolito challenges for a ball in the box and goes down, but Bailly got his legs to the ball and Clattenburg waves the appeals away.
80' 10 minutes to go - who will come out on top?
79' After a lengthy build up, De Bruyne takes the free-kick and sends it well over the bar.
78' Rooney concedes a poor foul on the edge of the box. City have a great chance here...
77' Nolito is clear! However, the whistle blows for offside and United breathe a sigh of relief.
76' NEARLY! De Bruyne lays the ball off to Silva on the edge of the box, and he curls a lovely left footed shot narrowly over the top left corner. End-to-end stuff as the game opens up.
74' HOW DID THAT STAY OUT?!!! Sane leads City's counter attack on the right, and produces a lovely through ball to De Bruyne on the run. The Belgian takes his shot first time and watches in agony as his effort cannons off the inside of the near post and dribbles narrowly near the goalline.
73' ALMOST! A lovely long ball from De Gea to Herrera on the left wing ends with his cross towards an unmarked Rashford being cleared by Fernandinho.
71' WHAT A SAVE! De Bruyne sends in a peach of a cross from a short corner, and Fernandinho volleys the ball towards the bottom corner, only for De Gea to make a save. Bailly clears the ball for a another corner to prevent Otamendi from clearing the rebound. From the next corner, Fellaini clears De Bruyne's cross for another corner.
70' THE BALL IS IN THE NET! Old Trafford cheers as Rashford's shot deflects off Zlatan and wrongfoots Bravo as it goes into the net, but the Swede was offside and the goal is ruled out.
67' David Silva releases the pressure on City with a well earned foul, drawing Luke Shaw to make a reckless tackle. De Bruyne stands over the resulting free-kick, but his delivery is poor and United clear with ease.
66' ALMOST! Classic long ball - Route 1 football as Fellaini flicks the ball on to Zlatan on the edge of the box, but his first-time volley flies over.
64' A spell of Manchester City possession ends with Leroy Sane misplacing a touch and allowing Shaw to clear. Moments later, Kolarov's shot is blocked, as City turn up the heat.
62' Ironic cheers ring out at Old Trafford as Bravo collects a lofted free-kick from Rooney.
60' Leroy Sane comes on for his debut, replacing Raheem Sterling. It's anyone's guess where he will play.
58' WAS THAT HANDBALL? United scream for another penalty as the Red Devils counter down the right with Rooney and Valencia. The Ecuadorian's cross clatters off Otamendi's back, with Clattenburg waving away the appeals yet again.
56' WHAT IS HE DOING?! Bravo tries a cheeky dummy and makes a mess of it, with the ball running towards Rooney, and the Chilean lunges in and gets the ball, but follows through on Rooney, leaving him injured. Clattenburg waves away the penalty appeals.
54' City have managed to regain possession and have restored calm to their midfield after Fernando has come on, as they slow the game down with plenty of square passes.
53' Well this is a BIG change! Guardiola hauls off Iheanacho for Fernando, with De Bruyne playing the false nine role.
52' Herrera holds off a couple of City challenges and earns a free kick in midfield. Mourinho's substitutes are working. Meanwhile Fellaini goes into the book for a stray elbow on Kolarov.
51' Otamendi writhes around in pain as Zlatan goes into the book for a sneaky clip on his heels.
50' United are pressing the ball much higher up the pitch, with Rooney and Rashford making merry on either wing. Mourinho's changes have worked, with City struggling to get out of their half. Bravo's goal kick is straight at De Gea.
48' SHOT! Ibrahimovic controls a cross from the right with his chest before crashing a volley over the crossbar. United have started the second half on the front foot!
46' WHAT A MISS! Rashford leaves his marker on the dust on the left wing, before clipping a ball to Zlatan in the box, but Kolarove does well to put him off and the Swede volleys over the bar!
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|14||West Ham United||33||8||11||14||-18||35|
|20||West Bromwich Albion||34||4||12||18||-25||24|