Pittsburgh vs. Notre Dame prediction, odds and picks - October 28 | NCAAF season 2023

The Pittsburgh Panthers head to Notre Dame to play the Fighting Irish on Saturday, Oct. 28 at 3:30 p.m. ET. Pittsburgh is coming off a 21-17 loss to Wake Forest and the week before that handed Louisville their first loss of the season.

Meanwhile, Notre Dame is coming off their open week; In Week 7, they beat the USC Trojans 48-20. Prior to that, the Fighting Irish lost 33-20 to Louisville.

Pittsburgh vs. Notre Dame: Match Details

Fixture: Pittsburgh Panthers (2-5) vs. Notre Dame Fighting Irish (6-2)

Date & Time: Saturday, Oct. 28 at 3:30 p.m. ET

Venue: Notre Dame Stadium

Pittsburgh vs. Notre Dame: Betting Odds

Spread

Pittsburgh +20.5 (-108)

Notre Dame -20.5 (-112)

Moneyline

Pittsburgh +850

Notre Dame -1450

Total

Over 44.5 (-110)

Under 44.5 (-110)

Pittsburgh vs. Notre Dame Picks

The Pittsburgh Panthers have played some decent offense and quarterback Christian Veilleux has done well. The Canadian transferred from Penn State and is in his first year at Pitt. Veilleux has done well in the passing game so take him to throw over 1.5 passing touchdowns. In his three starts, Veilleux has thrown over 1.5 touchdowns in each game.

The Notre Dame Fighting Irish, meanwhile, are led by Sam Hartman, who has been up-and-down this season. In this game, Notre Dame will rely on its running game as Audric Estime has been solid this season. He's currently averaging 98.38 rushing yards per game, so take him over as Pitt's defense has also struggled this season.

Pittsburgh vs. Notre Dame head-to-head

Pittsburgh and Notre Dame is a storied college football rivalry that began in 1909. The Fighting Irish lead the all-time series 49-21-1 and are currently on a three-game win streak.

Pittsburgh vs. Notre Dame Prediction

Notre Dame had two tough losses to Ohio State and Louisville, which ended their chance of making the college football playoff. However, this is still a very good game for the Fighting Irish to cruise to a win here.

Pittsburgh's defense is a concern against this Fighting Irish offense that is coming off a bye week.

Prediction: Notre Dame beats Pittsburgh by double digits.