They scored a number of points off errors from the racquets of the French players - but in the second set were thoroughly outplayed - with the French pair fighting back at the end of Set 1.
Sania Mirza and Barbora Strycova have been in fine form since they came together, and they came into the US Open having won a title.
Second set is easy peasy for French Open 2016 champions Caroline Garcia and Kristina Mladenovic! They beat 7th seeds Sania Mirza and Barbora Strycova 7-6, 6-1.
Up an early break of serve, Mladenovic and Garcia led 3-0 before rain saw the players led off court.
Play has been suspended as rain hits the court!
Second set's underway and Mladenovic-Garcia are already up a break. They lead 2-0 right now after having opened serve for this set.
Game and set to Garcia and Mladenovic, who win 7-6 (2).
Mirza sends that volley pummeling towards Garcia, who can't combat it. She nets it, but they still lead the Indo-Czech pair 5-2.
It's looking bleak for Mirza and Strycova in the tiebreaker. The French pair lead 5-1.
Brilliant comeback from the French pair! After breaking back, they've clawed their way back to force a first-set tiebreaker.
Mirza and Strycova are now relying on unforced errors from their rivals for points - but nevertheless, they lead 6-5 and Mladenovic/Garcia now serve to stay in the set.
This is going a bit south for Mirza and Strycova after a whopper of a start. They took the early break, but a break back and some solid holds of serve mean scores are now level at 5-5.
Looks like there's a big fight back as Garcia and Mladenovic now break back for 4-5 in the first!
Wow. They've held on have Garcia and Mladenovic, and Mirza and Strycova now serve for the set.
That's a beautiful drop shot from 22-year-old Caroline Garcia! She leaps high for that and smashes it down with ease.
SET POINT as Mirza and Strycova look set to take the break... but their rivals fight back for deuce!
Between Mirza's forehand and Strycova's backhand, the pair are making a meal of the French Open winners. They hold for a 5-2 lead, and now Mladenovic and Garcia will serve to stay in the set.
The French pair hold a quick service game but still trail 2-4!
And they HOLD! 4-1 to Mirza and Strycova and this set is incredibly one sided right now..
And it's Mirza and Strycova with the first break of serve! They lead 3-1.
Uncharacteristically high number of errors from Mladenovic and Garcia give free points to Mirza/Strycova.
That's a BEAUTIFUL forehand winner from Mirza! The pair take a 2-1 lead - without conceding a single point in that game.
Both teams hold. Scores now 1-1.