Syracuse Orange vs. Notre Dame Fighting Irish Odds, Line, Predictions, and Picks- October 29 | 2022 NCAA Football Season

Can Michael Mayer lead the Notre Dame Fighting Irish to an upset over Syracuse?
Can Michael Mayer lead the Notre Dame Fighting Irish to an upset over Syracuse?

The Notre Dame Fighting Irish who are battling through a rebuilding year travel to take on the formidable Syracuse Orangemen. The Fighting Irish of Notre Dame battled back following an 0-2 start to get back over .500 at 4-3.

The Irish have talent on both sides of the ball, but the offense lacks enough firepower to threaten the better teams in the country.

Speaking of firepower, the Syracuse Orangemen have been a revelation this season. Syracuse pushed Clemson to the brink last week and should have pulled off the upset. The Orangemen look to rebound and continue their strong season to make a case for a Major Bowl bid.

The betting odds and predictions are below:

To upset Syracuse, the Notre Dame Fighting Irish must identify an offensive balance. TE Michael Mayer is a match-up nightmare for the opposition. The Irish must force targets in Mayer's direction. Notre Dame doesn't have much firepower on the outside at the receiver position. The Irish struggle to stretch the field, making Michael Mayer all more important in their offensive gameplan.

Syracuse possesses the balance of a true contender. RB Sean Tucker is extraordinary and can break a long run at any given time. Combine Tucker's game-breaking ability with the versatility of QB Garrett Shrader. The Syracuse signal-caller is a nightmare match-up for a vulnerable Irish defense.

Syracuse Orangemen vs. Notre Dame Fighting Irish Game Details

Fixture: Notre Dame Fighting Irish @ Syracuse Orangemen

Date and Time: Saturday, October 29, 12:00 PM ET

Venue: JMA Wireless Dome, Syracuse, NY

Syracuse Orangemen vs. Notre Dame Fighting Irish Best Pick:

I don't see Notre Dame holding down the Syracuse offense for long. Syracuse can hurt them in so many ways. Anticipate the Irish loading up the box to take away the run game led by Sean Tucker. Garrett Shrader will take to the air, punishing an overmatched Notre Dame secondary.

Garrett Shrader: Passing Yards: Over 220.5

Syracuse Orangemen vs. Notre Dame Fighting Irish Final Prediction

Had Syracuse completed the victory over Clemson a week ago, this would have been a HUGE letdown spot for them. Seeing that they squandered a lead, anticipate the Syracuse program taking care of business this week at home.

Notre Dame doesn't have the talent across the board to compete with the top programs in the country. Syracuse deserves recognition as one of the top teams in the land.

Syracuse Orangemen: -2.5 (-110)

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Edited by Mudeet Arora