New England Revolution entertain Pumas UNAM at the Gillette Stadium in the first leg quarter-final fixture of the CONCACAF Champions League on Wednesday.The home side will be appearing in the 2022 edition of the competition for the first time on Wednesday as they automatically qualified for this stage of the competition as their opponents in the round of 16, Cavaly AS dropped out last month.The visiting side secured a 6-3 win on aggregate over Costa Rican club Deportivo Saprissa as they secured a 4-1 win at home in the second leg. The hosts secured their first win of the MLS 2022 campaign at home against Dallas while the Liga MX side are winless in their last three games, suffering a 3-2 away loss at Santos Laguna most recently.Scotiabank Concacaf Champions League@TheChampionsScotiabank Concacaf Champions League is back this week! Which matchups are you watching this week? 🍿 #SCCL2210:30 AM · Mar 7, 2022802117Scotiabank Concacaf Champions League is back this week! Which matchups are you watching this week? 🍿 #SCCL22 https://t.co/greGHwvW9YNew England Revolution vs Pumas UNAM Head-to-HeadThe two clubs have squared off just once in competitive fixtures so far. That meeting came in the group stage fixture of the erstwhile North American SuperLiga. The hosts, who were the eventual runners-up in the 2010 edition, secured a 1-0 win.New England Revolution form guide (MLS): W-DPumas UNAM form guide (all competitions): L-D-W-D-DNew England Revolution vs Pumas UNAM Team NewsNew England RevolutionThe Revs will be without the services of two goalkeepers as Brad Knighton has been ruled out with a head injury. Arsenal-bound Matt Turner has not featured in the two MLS games so far with an undisclosed issue and remains doubtful for this game.New England Revolution@NERevolutionBruce stands alone revolutionsoccer.net/news/the-great…11:28 AM · Mar 6, 2022734Bruce stands alone 🔝revolutionsoccer.net/news/the-great…Injured: NoneDoubtful: Brad Knighton, Matt TurnerSuspended: NonePumas UNAMFavio Álvarez, Alek Álvarez, Jorge Ruvalcaba, and Amaury García have been ruled out for the visiting side since last month with injuries. They face fitness tests ahead of the trip to the USA. Jerónimo Rodríguez became the latest casualty for Auriazules. Injured: Jerónimo RodríguezDoubtful: Favio Álvare, Alek Álvarez, Jorge Ruvalcaba, Amaury GarcíaSuspended: NoneNew England Revolution vs Pumas UNAM Predicted XINew England Predicted XI (4-3-1-2): Earl Edwards Jr. (GK); DeJuan Jones, Omar Gonzalez, Andrew Farrell, Brandon Bye; Matt Polster, Thomas McNamara, Sebastian Lletget; Carles Gil; Gustavo Bou, Adam BuksaPumas UNAM Predicted XI (4-3-3): Alfredo Talavera (GK); Alan Mozo, Arturo Ortiz, Nicolás Freire, Efraín Velarde; Leonel López, Ricardo Galindo, Cristian Battocchio; Sebastián Saucedo, Juan Dinenno, Washington CorozNew England Revolution vs Pumas UNAM PredictionThe hosts have looked solid in their two MLS games so far, scoring three goals, but have conceded two goals as well. The Mexican side have struggled with injuries in their recent fixtures, picking up just two wins in their last eight games across all competitions.Though they have had four more days than the hosts to prepare for the game, they might come up short in this away game.Prediction: New England Revolution 1-0 Pumas UNAM