Cristiano Ronaldo and Manchester United were handed a shock 1-0 defeat by Wolves in the Premier League on Monday. The Red Devils flattered to decieve in front of their own fans at Old Trafford in a game where Cristiano Ronaldo donned the captain's armband.The Portuguese superstar stepped in to lead Manchester United in the absence of the injured Harry Maguire, but failed to inspire his team. Cristiano Ronaldo cut a frustrating figure for the majority of the game as Wolves earned a well-deserved win.Bruno Lage's visitors were proactive from the get-go and dominated Manchester United. Wolves won the battle in midfield and were only denied a goal in the first half due to David de Gea's brilliance. The Spaniard produced saves off Ruben Neves, Daniel Podence and Nelson Semedo to keep the scoreline at 0-0.In an attempt to introduce some flair into the game, Ralf Rangnick called on Bruno Fernandes from the bench in the second half. The midfielder came closest to scoring for Manchester United as he crashed an attempt onto the woodwork shortly after the hour mark.SuperSport 🏆@SuperSportTVWolves win at Old Trafford for the first time since 1980, almost 42 years ago 😳1:01 AM · Jan 4, 2022566123Wolves win at Old Trafford for the first time since 1980, almost 42 years ago 😳 https://t.co/mPn4nKrEN0Cristiano Ronaldo then found the back of the net from a set-piece, but the Manchester United captain was rightfully adjudged offside. Romain Saiss then rattled the woodwork with his free-kick for Wolves before the visitors grabbed a late winner.Joao Moutinho's late strike condemned Manchester United and Cristiano Ronaldo to defeatThe only goal of the game came through Cristiano Ronaldo's Portuguese counterpart Joao Moutinho. Wolves' veteran midfielder pounced on a loose clearance and fired a shot into the back of the net from the edge of the area in the 82nd minute.The low shot fired into the far corner provided De Gea with little chance of keeping the ball out of the net.Manchester United were awarded a free-kick on the edge of Wolves' penalty area right at the end. However, Fernandes' excellent attempt was met with an impressive save from Jose Sa. The Wolves custodian kept the effort out at full stretch and celebrated passionately with his teammates as the referee blew the full-time whistle.Football Daily@footballdaily🐺 José Sá screams with joy at full-time after a big save to help beat Man United12:58 PM · Jan 4, 202264956🐺 José Sá screams with joy at full-time after a big save to help beat Man United https://t.co/jfqPpDVcWwThe result proved to be Wolves' first away win at Manchester United since 1980. Understandably, the defeat raised questions at Cristiano Ronaldo and company. In all fairness, the Red Devils were never really at the races as Rangnick suffered his first defeat as Manchester United boss.Without further delay, let's take a closer look at the best reactions on Twitter as Wolves recorded a memorable win:zayne@zayneswrldRonaldo definitely not as good or even the same player he used to be. Every time he gets the ball he passes it back, he doesn’t look to take on players or even run at them anymore. I think he should just call it a day #MUNWOL12:12 PM · Jan 4, 2022Ronaldo definitely not as good or even the same player he used to be. Every time he gets the ball he passes it back, he doesn’t look to take on players or even run at them anymore. I think he should just call it a day #MUNWOLAdam Lewis@AdamjamesLewis7United have about as much urgency as a Tesco Express security man working a bank holiday #slow #MUNWOL12:12 PM · Jan 4, 2022United have about as much urgency as a Tesco Express security man working a bank holiday #slow #MUNWOLGreg Constable@gregconstableMan Utd are so dull to watch now. There aren’t any players in that team that excite the crowd when they get on the ball 😴🙄 #MUNWOL12:12 PM · Jan 4, 2022Man Utd are so dull to watch now. There aren’t any players in that team that excite the crowd when they get on the ball 😴🙄 #MUNWOLChumet@Chumet_A discussion will need to be had of how Ronaldo is hindering Greenwood's progress #MUNWOL12:12 PM · Jan 4, 20221A discussion will need to be had of how Ronaldo is hindering Greenwood's progress #MUNWOLMegan@Meganss96The fact Phil Jones can walk back in after 2 years and be one of the better players must be pretty worrying #MUNWOL12:11 PM · Jan 4, 20222The fact Phil Jones can walk back in after 2 years and be one of the better players must be pretty worrying #MUNWOLLanre Reactivated@Coolboy_LanreMan Utd have been insanely poor in this game. This is not gengen pressing football. This is depressing football.#MUNWOL12:11 PM · Jan 4, 20221Man Utd have been insanely poor in this game. This is not gengen pressing football. This is depressing football.#MUNWOLNeondeck@thegudbadguyThis man United team is just all about individual brilliance, no team spirit.. not good enough #MUNWOL12:11 PM · Jan 4, 2022This man United team is just all about individual brilliance, no team spirit.. not good enough #MUNWOLGareth@Gareth_UtdI bet Ralf is thinking "this isn't how I instructed these clowns to play"#MUFC #MUNWOL12:14 PM · Jan 4, 2022133I bet Ralf is thinking "this isn't how I instructed these clowns to play"#MUFC #MUNWOLBobbyTerry@BobbyTerry42384Never seen a side so poor at passing. #MUNWOL #mufc12:16 PM · Jan 4, 2022Never seen a side so poor at passing. #MUNWOL #mufcJac FT@JAC_FT1Please can we give Ronaldo back to Juventus and bring Ole back? We're playing with 10 men #MUNWOL12:45 PM · Jan 4, 2022Please can we give Ronaldo back to Juventus and bring Ole back? We're playing with 10 men #MUNWOLChristian@_christianjb#MUNWOL1:09 AM · Jan 4, 20221#MUNWOL https://t.co/KpvA6s3WsEBen Floto@ben_flotoNeves walks into any midfield in the league #Wolves #MUNWOL1:09 AM · Jan 4, 2022Neves walks into any midfield in the league #Wolves #MUNWOLquasi kwarteng@zarndeepRonaldo can’t even go and ask Harry Kane for advice on how to get out the Europe conference league group #MUNWOL1:09 AM · Jan 4, 2022Ronaldo can’t even go and ask Harry Kane for advice on how to get out the Europe conference league group #MUNWOLCPA Amkoah Elijah@CPA_AmkoahMan United is the biggest fraud in the world. OLE was never the problem after all. #MUNWOL1:09 AM · Jan 4, 2022Man United is the biggest fraud in the world. OLE was never the problem after all. #MUNWOLNoxwin@noxwin12GOAL❗️Manchester United 0 - 1 Wolves⚽️82`Joao MoutinhoLive Odds : bit.ly/3vWIxfG#PremierLeague #MUNWOL12:45 PM · Jan 4, 20224GOAL❗️Manchester United 0 - 1 Wolves⚽️82`Joao MoutinhoLive Odds : bit.ly/3vWIxfG#PremierLeague #MUNWOLhttps://t.co/VhSBi6RhpOAndrew Marley@drpatuti#MUNWOL12:45 PM · Jan 4, 2022#MUNWOL https://t.co/Ab3LsXO5ucA’ Kenneth.@Addoflash1Cristiano Ronaldo vs Wolves highlights.1:13 AM · Jan 4, 2022Cristiano Ronaldo vs Wolves highlights. https://t.co/LtuZ6r1kRcAdam@AD4MFTWCristiano Ronaldo highlights vs Wolves | Greatest Player of All Time?1:12 AM · Jan 4, 2022Cristiano Ronaldo highlights vs Wolves | Greatest Player of All Time? https://t.co/WOUhsECnDfTwinch@madoreIVCristiano Ronaldo is becoming a liability to the club. A risk we can't ignore. Manchester United in 2022.1:12 AM · Jan 4, 20221Cristiano Ronaldo is becoming a liability to the club. A risk we can't ignore. Manchester United in 2022.Ron GHOST@RonGHOST3Cristiano Ronaldo will be playing Europa soonMark my words😂😂🤣1:11 AM · Jan 4, 2022Cristiano Ronaldo will be playing Europa soonMark my words😂😂🤣Raymond@Raymidey4UCristiano Ronaldo has never lost a club game being captain.NobodyThat's where man united comes in1:11 AM · Jan 4, 2022Cristiano Ronaldo has never lost a club game being captain.NobodyThat's where man united comes in https://t.co/zpUqK2mhSGAadoo @AadozoCristiano Ronaldo is a liability and he's destroying Manchester United just like destroyed Juventus.1:11 AM · Jan 4, 2022Cristiano Ronaldo is a liability and he's destroying Manchester United just like destroyed Juventus. https://t.co/oq3LWNMZeHJulian@jre9324Absolutely thrilled that Cristiano Ronaldo will be attending Wolves training tomorrow, as he’s in Coady’s back pocket for the foreseeable future.1:10 AM · Jan 4, 20222Absolutely thrilled that Cristiano Ronaldo will be attending Wolves training tomorrow, as he’s in Coady’s back pocket for the foreseeable future.Gary Neville@GNev2It’s not good. It really isn’t!12:46 PM · Jan 4, 2022192851337It’s not good. It really isn’t!RB🤺🇦🇷@messaitamaManchester United's decision to sign back Cristiano Ronaldo twitter.com/GNev2/status/1…Gary Neville@GNev2It’s not good. It really isn’t!1:09 AM · Jan 4, 202211327It’s not good. It really isn’t!Manchester United's decision to sign back Cristiano Ronaldo twitter.com/GNev2/status/1…Ty Bracey@TyBraceyCristiano Ronaldo hasn’t got a chance against Ezri Konsa let’s be honest1:09 AM · Jan 4, 2022624Cristiano Ronaldo hasn’t got a chance against Ezri Konsa let’s be honest