#1 Conor McGregor
The biggest name in MMA against one of the biggest names in WWE. A clash for the ages. When it comes to Conor McGregor vs. Samoa Joe, the chance for the Samoan to choke out the Irishman is minuscule but it is still indeed there.
For all of McGregor's striking brilliance, it is on the ground that he suffers the most and this is where Joe excels. If he can keep away from that absolute cannon of a left-hand which is McGregor's go to weapon, then Joe is in with a real shout of causing the biggest upset in MMA history.
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All three of McGregor's losses in his MMA career have been submissions including his most recent one to Nate Diaz which was, as you might have guessed, the rear-naked choke.
Keep away from the punches, take Conor down, choke him out. Easy? Hell no. Possible? Yes, it is.