Seattle Sounders will host Tigres UANL at Lumen Field in the quarterfinals of the Leagues Cup on Wednesday.The home side come into the game on the back of a 1-1 draw with FC Dallas in an MLS fixture on Friday. Fredy Montero and Franco Jara scored second-half goals to ensure both sides shared the spoils.UANL Tigres also played out a 1-1 draw with Santos Laguna in a Liga MX fixture on Sunday. Fernando Gorriaran and Carlos Salcedo scored in each half to share the points at fulltime.The Leagues Cup is a joint initiative between the US and Mexico football federations and began in 2019, with this being the second edition. Eight teams are disputing the 2021 edition, with four clubs coming from each nation.Seattle Sounders vs Tigres UANL Head-to-HeadBoth sides met in the quarterfinals of the 2013 CONCACAF Champions League and each won the home leg of the tie, with Sounders progressing 3-2 on aggregate.One of the most memorable goals in Sounders FC history 🚀@Djimi_Traore19 scored this stunner the last time out against Tigres! pic.twitter.com/D1grfeCwR6— Seattle Sounders FC (@SoundersFC) August 8, 2021The hosts are currently on a poor run of form that has seen them win just one of their last five games. Tigres are slightly better off, with two victories recorded in the same sequence.Seattle Sounders vs Tigres UANL Team NewsSeattle SoundersThe home side have four players ruled out of the fixture due to injury. Jordy Delem (knee), Stefan Frei (knee), Jordan Morris (knee) and Nouhou Tolo (groin) are all unavailable for selection.Injuries: Jordy Delem, Stefan Frei, Jordan Morris, Nouhou ToloSuspension: None View this post on Instagram A post shared by 🇺🇦 Club Tigres 7️⃣ 🏆 (@clubtigresoficial)Tigres UANLFrancisco Meza and Andre-Pierre Gignac have both been ruled out through cruciate ligament and ankle injuries respectively. Florian Thauvin was shown a straight red card in the draw with Laguna.Injuries: Francisco Meza, Andre-Pierre GignacSuspension: NoneSeattle Sounders vs Tigres UANL Predited XISeattle Sounders Predicted XI (5-4-1): Stefan Cleveland (GK); Jimmy Medranda, Shane O'Neill, Xavier Arreaga, Yeimar Gomez, Alexander Roldan; Fredy Montero, Joao Paulo, Kelyn Rowe, Cristian Roldan; Raul RuidiazTigres UANL Predicted XI (4-2-2-2): Nahuel Guzman (GK); Francisco Vanegas, Carlos Salcedo, Diego Reyes, Luis Rodriguez; Juan Cham, Rafael Carioca; Javier Aquino, David Ayala; Carlos Gonzalez, Nicolas LopezSeattle Sounders vs Tigres UANL PredictionNeither side is coming into this game in the best of form but the fact that this is a continental fixture could spur the players to bring their A-game.Tigres have what it takes to get the job done here, but we are predicting a home victory for Seattle Sounders with goals to be scored at both ends.Prediction: Seattle Sounders 2-1 Tigres UANLAlso See: Fabrizio Romano's Transfer Roundup: Chelsea pushing for major signing, updates on Lukaku and Kane's futures and more