Mariners vs. Twins: Game 4 prediction, odds, injuries, and picks

The Minnesota Twins are looking to end their four-game series against the Seattle Mariners on a high note at home. After dropping the first two matches, Minnesota rallied back during Wednesday's Game 3 as starter Joe Ryan and the bullpen limited the Mariners' offense to three base hits.

Simeon Woods Richardson is scheduled to be deployed by skipper Rocco Baldelli for the series-closer. The 24-year-old holds a 2-4 record with a 5.06 ERA across 10 starts this season. Meanwhile, the Mariners will start Emerson Hancock in hopes of claiming the series victory on the road. Hancock has a 3-3 card and a 5.43 ERA across 13 starts.

Mariners vs. Twins recent form and records

It has been a less-than-ideal few weeks for Rocco Baldelli's men. Minnesota has only won two of its last 10 games, leading to a disappointing 38-42 record after being on the heels of the division-leading Tigers for a majority of the campaign.

The Mariners, on the other hand, have posted a 41-38 record, which is the second-best in the American League West. Dan Wilson's team currently trails the Astros by 5.5 games but remains within the wild card spots.

Mariners vs. Twins odds

Money Line: SEA (+104), MIN (-114)

Run Spread: SEA -1.5 (+156), MIN +1.5 (-192)

Total Runs: O 8.5 (-120), U 8.5 (+101)

Mariners vs. Cubs injuries

SEA injury report

Ryan Bliss (2B): 60-day IL (biceps)
Victor Robles (RF): 60-day IL (shoulder)
Bryce Miller (SP): 15-day IL (elbow)
Gregory Santos (RP): 60-day IL (knee)
Collin Snider (RP): 15-day IL (forearm)

MIN injury report

Royce Lewis (3B): 10-day IL (hamstring)
Luke Keaschall (2B): 60-day IL (forearm)
Zebby Matthews (SP): 15-day IL (shoulder)
Pablo Lopez (SP): 60-day IL (teres major)

Mariners vs. Twins projected lineup

SEA projected lineup

J.P. Crawford (SS)
Julio Rodriguez (CF)
Cal Raleigh (C)
Jorge Polanco (DH)
Randy Arozarena (LF)
Luke Raley (1B)
Dominic Canzone (RF)
Ben Williamson (3B)
Cole Young (2B)
Emerson Hancock (SP, 3-3 | 5.43 ERA | 50 K)

MIN projected lineup

Byron Buxton (CF)
Matt Wallner (RF)
Willi Castro (LF)
Trevor Larnach (DH)
Ty France (1B)
Carlos Correa (SS)
Kody Clemens (2B)
Ryan Jeffers (C)
Brooks Lee (3B)
Simeon Woods Richardson (SP, 2-4 | 5.06 ERA | 46 K)

Mariners vs. Twins picks and game prediction

With either pitchers having less-than-ideal campaigns, the Mariners have the slight edge in terms of momentum. If they can hound Twins starter Simeon Woods Richardson from the get-go, the Mariners should comfortably take the series victory in the Twin Cities.

Run Line: SEA -1.5 (+156)

Total Runs: O 8.5 (-120)

Prediction: SEA wins, 6-4

About the author

Daniel Santiago is a journalist who has been reporting on baseball at Sportskeeda since 2022. He was drawn towards the sport after the underlying statistics and the analysis surrounding it grabbed his attention.

Daniel particularly enjoys furnishing reports about historic events in baseball and analyzing the game through a statistic-based outlook, based on Fangraphs and Baseball-Reference. This is in line with how he enjoyed watching baseball as a pastime. As a writer, he is very particular about cross-checking from reputable sources and doing his due diligence.

He became a lifelong Hideki Matsui fan after his exploits in the 2009 World Series for the New York Yankees. Among the current generation, Daniel's favorites include Shohei Ohtani and Jung Hoo Lee. Daniel is a huge follower of Asian baseball and both Ohtani and Lee have been in the top echelon of their respective leagues during their time with the NPB and KBO.

His favorite moment as a baseball fan was the final at-bat of the 2023 World Baseball Classic between Shohei Ohtani and Mike Trout. He believes there aren't many words to fittingly describe the intensity of the moment.

As an avid sports fan, Daniel watches other sports and Esports when not writing about baseball.

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Edited by Daniel Santiago

Mariners vs. Twins: Game 4 prediction, odds, injuries, and picks - June 26, 2025