The two sides had contrasting 2020-21 campaigns, with Real Madrid finishing second in the league behind Atletico Madrid, while Alaves finished 16th, four points off the relegation zone.
Alaves have been inconsistent in their pre-season campaign so far. However, Javier Calleja's side will go into the game off the back of a 1-0 win against Levante.
El Glorioso have strengthened well in the transfer market, bringing in the likes of Florian Lejeune, Toni Moya, Ivan Martin, Manu Garcia, Mamadou Loum and Facundo Pellestri. However, they will have the tough task against a strong Real Madrid side on Saturday.
This will be Carlo Ancelotti's first game back in charge of Real Madrid, and the Italian will be looking to start his tenure off with a win.
Los Blancos have had a terrible pre-season campaign, having not won either of their friendlies. The club will also have to cope with the loss of both Sergio Ramos and Raphael Varane, who left for PSG and Manchester United respectively earlier this summer.
However, the arrival of David Alaba is sure to provide a boost to their weakened backline.
Both sides will want to start their 2021-22 campaign off with a win, with Real Madrid looking to challenge for the La Liga title once again this season.
Alaves vs Real Madrid Head-to-Head
As expected, Real Madrid have dominated the head-to-head record between the two sides, winning four of their last five meetings, with Alaves winning the other.
Real Madrid came away as 4-1 winners the last time the two sides met back in January. A brace from Karim Benzema, along with goals from Casemiro and Eden Hazard, was enough to complete the rout, with Joselu getting on the scoresheet for Alaves.
Alaves Form Guide: yet to play
Real Madrid Form Guide: yet to play
Alaves vs Real Madrid Team News
Alaves' new signing Mamadou Loum picked up a thigh injury earlier this week and will miss the game on Saturday.
Apart from that, Javier Calleja will have a full-strength team to choose from for the game.
Injured: Mamadou Loum
Real Madrid will have a host of players unavailable for Saturday's game. Toni Kroos, Dani Carvajal, Ferland Mendy, Alvaro Odriozola and Dani Ceballos will all miss the game due to injury.
Meanwhile, Ancelotti will be sweating on the fitness of Eden Hazard, who is a doubt for the game. Karim Benzema has recovered from COVID-19 but is unlikely to start on Saturday.
Injured: Toni Kroos, Dani Carvajal, Ferland Mendy, Alvaro Odriozola, Dani Ceballos
Doubtful: Eden Hazard, Karim Benzema
Alaves vs Real Madrid Predicted XI
Alaves Predicted XI (4-4-2): Fernando Pacheco; Ruben Duarte, Florian Lejeune, Victor Laguardia, Martin Aguirregabiria; Luis Rioja, Pere Pons, Tomas Pina, Ivan Martin; Lucas Perez, Joselu
Real Madrid Predicted XI (4-3-3): Thibaut Coutois, Marcelo, David Alaba, Eder Militao, Lucas Vazquez; Casemiro, Federico Valverde, Luka Modric; Rodrygo, Vinicius Junior, Luka Jovic
Alaves vs Real Madrid Prediction
It's hard not to see Real Madrid winning this game, given the difference in quality between the two sides. However, Alaves should still make it difficult for Carlo Ancelotti's team.
We predict a well-contested matchup with Real Madrid coming out on top.
Prediction: Alaves 1-2 Real Madrid