The promoted side are seeking to put more daylight between them and the relegation zone as the season heads to a close.
Die Arminen are just a point clear of Hertha Berlin in 15th place, but with a game in hand. The capital side won't be in action for at least another week after an outbreak of COVID-19 in their camp.
Following a goalless draw at Augsburg on Saturday, Frank Kramer's side missed a chance to go three points clear of the relegation zone. However, their next opponents are in a worse position.
With just two wins all season, the Royal Blues are rock bottom in the Bundesliga, having accrued a meager 13 points from 29 games. They will be relegated with a defeat on Tuesday.
Arminia Bielefeld vs Schalke 04 Head-To-Head
In 18 clashes between the sides, the Royal Blues have a superior record with 12 wins, losing to Arminia only thrice.
That includes one this season, too, when Die Arminen secured a 1-0 victory at Gelsenkirchen.
Arminia Bielefeld Form Guide (all competitions): W-L-D-W-D
Schalke 04 Form Guide (all competitions): L-L-L-W-L
Arminia Bielefeld vs Schalke 04 Team News
Sergio Cordova and Reinhold Yabo are still in quarantine. Meanwhile, Masaya Okugawa (cramps) and Fabian Klos (foot) are nursing minor injuries and will be assessed ahead of kick-off.
Unavailable: Sergio Cordova and Reinhold Yabo
The Royal Blues have quite a few injury concerns with as many as seven players out injured. Kilian Ludewig's injury is long-term, having been out since December with a metatarsal fracture.
Nabil Bentaleb has been sidelined for a month with a groin problem but is expected to return next week.
Injured: Kilian Ludewig, Nabil Bentaleb, Steven Skrzybski, Matija Nastatic, Nassim Boujellab, Hamza Mendyl, and Levent Mercan
Arminia Bielefeld vs Schalke 04 Predicted XI
Arminia Bielefeld (4-3-3): Stefan Ortega; Cedric Brunner, Amos Pieper, Joakim Nilsson, Anderson Lucoqui; Nathan de Medina, Manuel Prietl, Fabian Kunze; Ritsu Doan, Sven Schipplock, Andreas Voglsammer.
Schalke 04 (3-5-2): Ralf Fahrmann; Benjamin Stambouli, Malick Thiaw, Timo Becker; Mehmet Aydin, Suat Serdar, Can Bozdogan, Omar Mascarall, Sead Kolasinac; Amine Harit, Klaas-Jan Huntelaar.
Arminia Bielefeld vs Schalke 04 Prediction
Schalke are stuck in such a rut that it's impossible to see them taking anything out of the game.
It should be a straight-forward victory for the home side.
Prediction: Arminia Bielefeld 2-0 Schalke