The Premier League returns for a second round of fixtures this weekend as an impressive Arsenal side takes on London rivals West Ham United in an intriguing derby at the Emirates Stadium. The Gunners have kicked off their campaign with an emphatic victory and will look to build on an excellent start to the season.West Ham were not at their best in their opening game and suffered a 2-0 defeat to Newcastle United last weekend. The Hammers need to improve under David Moyes and cannot afford to make sloppy mistakes against an efficient Arsenal side.The Gunners have benefitted immensely from Mikel Arteta's blend of tactical ingenuity and pragmatism and can make a genuine push for the Premier League top four this season. Arsenal have an excellent attacking force and a wealth of options in the midfield and are the favourites to win this game.Hitting the target 🎯Again. And again. And again. And again.🎮 Now playing: 𝗔𝘂𝗯𝗮𝗪𝗮𝘁𝗰𝗵 🎮— Arsenal (@Arsenal) September 17, 2020Arsenal vs West Ham United Head-to-HeadArsenal and West Ham are two of the oldest Premier League clubs from London and the two sides have played a total of 142 fixtures against each other. Arsenal predictably have the historical upper hand and have won 68 games as opposed to West Ham's 35 victories.Arsenal managed a hard-fought 1-0 victory in the previous meeting between these two sides a few months ago. Alexandre Lacazette scored a late goal on the day and is likely to feature in the starting eleven this weekend.Arsenal form guide in the Premier League: WWest Ham United form guide in the Premier League: LAlso Read: Brighton 1-3 Chelsea: Player Ratings as new-look Blues record hard-fought victory | Premier League 2020-21Arsenal vs West Ham United Team NewsArsenal defender Shkodran Mustafi is injuredArsenalArsenal have one of the longest injury lists in the Premier League and will go into the new campaign without four key players. Shkodran Mustafi, Gabriel Martinelli, Pablo Mari, and Calum Chambers are injured and have been ruled out of this game. David Luiz and Granit Xhaka are recovering from niggles and remain a doubt for this game.Injured: Shkodran Mustafi, Gabriel Martinelli, Pablo Mari, Calum ChambersDoubtful: David Luiz, Granit XhakaSuspended: NoneManuel Lanzini is back for West HamWest Ham UnitedManuel Lanzini has finally recovered from his injury and is likely to feature in the midfield against Arsenal. West Ham have a fully-fit squad and will have to be at their best to stand a chance against the Gunners.Injured: NoneDoubtful: NoneSuspended: NoneArsenal vs West Ham United Predicted XIArsenal Predicted XI (3-4-3): Bernd Leno; Kieran Tierney, Gabriel Magalhaes, Rob Holding; Bukayo Saka, Dani Ceballos, Mohamed Elneny, Hector Bellerin; Willian, Alexandre Lacazette, Pierre-Emerick AubameyangEvery @Aubameyang7 goal. Right here. All 72* of them! 🔥* 𝘚𝘰 𝘧𝘢𝘳... 😉 pic.twitter.com/2CqoJqcSfk— Arsenal (@Arsenal) September 16, 2020West Ham Predicted XI (4-2-3-1): Lukasz Fabianski; Ryan Fredericks, Issa Diop, Angelo Ogbonna, Aaron Cresswell; Tomas Soucek, Declan Rice; Manuel Lanzini, Mark Noble, Felipe Anderson; Michail AntonioArsenal vs West Ham United PredictionArsenal have experienced an extraordinary resurgence under Mikel Arteta over the past few months and have a distinct upper hand going into this fixture. With Manuel Lanzini and Felipe Anderson in their ranks, however, West Ham are not an easy team to defeat and can make life difficult for the Gunners.Pierre-Emerick Aubameyang and Alexandre Lacazette are in excellent form and both Willian and Gabriel Magalhaes excelled on their Arsenal debuts last week. The Gunners are firing on all cylinders at the moment and should be able to win this game.Prediction: Arsenal 3-1 West Ham UnitedAlso Read: Fulham 0-3 Arsenal: Player Ratings as Gunners make massive statement with emphatic victory | Premier League 2020-21