In the semifinal second leg of the 2022 CONCACAF Champions League, Cruz Azul will host Pumas UNAM at the Estadio Azteca on Wednesday morning.Cruz were beaten 2-1 in the first leg last week. They found themselves two goals down at the break before Christian Tabo came off the bench to score a late crucial away goal, his maiden strike for the club.The home team are six-time winners of the CONCACAF Champions League, last lifting the trophy in the 2013-14 season. They were knocked out at this stage of the competition last season by Monterrey and will hope for better luck this time around.Pumas UNAM hold the advantage ahead of the return leg on Wednesday. Juan Dinenno continued his impressive showing in the competition, scoring a third straight home brace. View this post on Instagram Instagram PostPumas will now look to complete the job this week and advance to the final as they look to end their 33-year wait for a continental title.Cruz Azul vs Pumas UNAM Head-to-HeadThere have been 71 meetings between Cruz and Pumas. The hosts have won 31 of those games, while the visitors have won 18. There have been 22 draws between the two teams.Cruz Azul Form Guide (all competitions): D-L-W-L-D.Pumas UNAM Form Guide (all competitions): D-W-W-D-L.Cruz Azul vs Pumas UNAM Team NewsCruz AzulJuan Escobar came off injured last week, while Carlos Rodriguez picked up an injury in the subsequent game. The two men are set to miss out on this midweek clash, while 41-year-old goalkeeper Jesus Corona is on the recovery path from injury but is a doubt for the game.Injured: Juan Escobar, Carlos RodriguezDoubtful: Jesus Corona, Angel Romero.Suspended: None.Unavailable: None.Pumas UNAM Marco Garcia and Amaury Garcia are both injured and are not expected to play against Cruz Azul on Wednesday.Injured: Marco Garcia, Amaury Garcia.Doubtful: None.Suspended: None.Unavailable: None.Cruz Azul vs Pumas UNAM Predicted XIsCruz Azul (4-4-1-1): Sebastian Jurado (GK); Alejandro Mayorga, Pablo Aguilar, Luis Abram, Joaquin Martinez; Jose Rivero, Erik Lira, Rafael Baca, Angel Romero; Romulo Otero; Santiago Gimenez, View this post on Instagram Instagram PostPumas UNAM (4-3-3): Alfredo Talavera (GK); Alan Mozo, Arturo Ortiz, Nicolas Freire, Efrain Velarde; Favio Alvarez, Leonel Lopez, Higor Meritao; Rogerio, Juan Dinenno, Washington Coroz,$1,100 First Bet Insurance at CaesarsCruz Azul vs Pumas UNAM PredictionCruz have struggled for form lately, winning just one of their last five games across competitions. They are, however, on a three-game winning streak on home turf and will look to capitalise on their home advantage this week.Pumas, meanwhile, are on a four-game unbeaten run across competitions and have lost just one of their last six. They have one foot in the final already and should complete the task this week.Prediction: Cruz Azul 1-1 Pumas UNAM.