Cruz Azul and Santos Laguna return to Liga MX action on Sunday following their midweek CONCACAF Champions League fixtures.The hosts emerged victorious in the round of 16 fixtures against Forge FC. With a 3-1 win in the second leg at home, Cruz Azul secured a 4-1 win on aggregate. Santos Laguna saw their one-goal lead from the first leg overturned as Montreal recorded a 3-0 win on Wednesday.Both clubs have endured contrasting fortunes in the league, with Cruz Azul recording four wins while the visitors have suffered four losses and are the only side without a win in the Mexican top-flight.Liga BBVA MX@LigaBBVAMX¿Es centro delantero? 🤔3er tanto en los últimos 4 partidos para Juan Escobar con @CruzAzul ¡¡Gran desempeño del DEFENSOR de 'La Máquina'!! @TheChampions7:55 AM · Feb 25, 2022102753¿Es centro delantero? 🤔9️⃣3er tanto en los últimos 4 partidos para Juan Escobar con @CruzAzul ¡¡Gran desempeño del DEFENSOR de 'La Máquina'!! 👏@TheChampions https://t.co/N22DkmCFhKCruz Azul vs Santos Laguna Head-to-HeadThe two clubs have squared off 60 times across all competitions since 1996. The hosts have been the better side with 25 wins, while the visitors are also not far behind with 21 wins. The spoils have been shared 14 times between the two sides.They last met at the Estadio Corona in August in the Apertura phase. The two sides squared off in the two-legged title decider in the 2021 Clausura. La Máquina secured a 2-1 win on aggregate to lift the league title.Cruz Azul form guide (all competitions): W-W-W-L-WSantos Laguna form guide (all competitions): L-D-W-L-LCruz Azul vs Santos Laguna Team NewsCruz AzulThe hosts have a clean bill of health at the moment and there are no suspensions for them either.CRUZ AZUL@CruzAzulMAÑANA JUEGA LA MÁQUINA 🎟 bit.ly/CAZ_SAN9:44 AM · Feb 26, 20221987106MAÑANA JUEGA LA MÁQUINA 🚂🎟 bit.ly/CAZ_SAN https://t.co/45UvbldmXvInjured: NoneDoubtful: NoneSuspended: NoneSantos Laguna Ayrton Preciado suffered a fractured tibia in the World Cup qualifying campaign with Ecuador and has been ruled out for the remainder of the season.Injured: Ayrton PreciadoDoubtful: NoneSuspended: NoneCruz Azul vs Santos Laguna Predicted XICruz Azul Predicted XI (4-2-3-1): José de Jesús Corona (GK); Alejandro Mayorga, Pablo Aguilar, Julio César Domínguez, Juan Escobar; Érik Lira, Rafael Baca; Uriel Antuna, Santiago Giménez, Carlos Alberto Rodríguez; Bryan AnguloSantos Laguna Predicted XI (5-4-1): Carlos Acevedo (GK); Carlos Orrantia, Felix Torres, Doria, Omar Campos, Hugo Rodríguez; Alan Cervantes, Fernando Gorriaran, Brian Lozano, Leonardo Suárez; Ignacio JeraldinoCruz Azul vs Santos Laguna PredictionCruz Azul have the joint-best defensive record in the league, having let in five goals so far. Guerreros are without a win in the league and have the worst-attacking record in the division.The visiting side have just one win in their last six games against the hosts and, given their current form, might struggle here. A win for the hosts seems to be the likely outcome here.Prediction: Cruz Azul 2-0 Santos Laguna