Los Canaleros beat the Caribbean side 2-1 at home on Saturday night to draw first blood and take a small advantage into next week's clash.
Alberto Quintero and Cecilio Waterman scored in the second half for the hosts. However, Rangelo Janga pulled one back for Guus Hiddink's side with just four minutes of normal time remaining.
The goal gave them a massive lifeline and they can advance into the third round of the qualifiers with a narrow 1-0 victory. However, Curacao will be wary of conceding the first goal as that would make their task harder.
Curacao vs Panama Head-To-Head
Panama's 2-1 victory against Curacao last week was just their third in history from nine games against the Caribbean outfit. Curacao remain ahead in terms of their head-to-head record with four wins over Panama.
Curacao Form Guide (all competitions): W-W-L-D-L
Panama Form Guide (all competitions): W-W-W-D-W
Curacao vs Panama Team News
Given that they need to score goals in the game, Guus Hiddink might opt to play a more attacking side in this match. Elson Hooi could come into the starting XI to provide width from the right flank and Gervane Kastaneer may be introduced on the left.
Janga, who scored their only goal of the match last time, might retain his place in the side.
Luis Mejia made an error which allowed Curacao back in the game, so the more experienced Jose Calderon might replace him for the second leg. Armando Cooper, the veteran midfielder with more than 100 caps to his name, might also follow suit after only coming off the bench in the last game.
Curacao vs Panama Predicted XI
Curacao (3-4-3): Eloy Room; Jurien Gaari, Suently Alberto, Cuco Martina; Kenji Gorre, Jarchinio Antonia, Leandro Bacuna, Michael Maria; Elson Hooi, Rangelo Janga, Gervane Kastaneer.
Panama (4-2-3-1): Jose Calderon; Michael Murillo, Harold Cummings, Andres Andrade, Eric Davis; Armando Cooper, Anibal Godoy; Alberto Quintero, Edgar Barcenas, Jose Luis Rodriguez; Gabriel Torres.
Curacao vs Panama Prediction
Panama aren't out of the woods yet as Curacao still have a chance to turn this tie around. However, more experience and goals in the other camp means the Canal Men won't easily be defeated.
We're predicting a low-scoring draw with the visitors to advance into the next round.
Prediction: Curacao 1-1 Panama
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