Genk will welcome Anderlecht to the Cegeka Arena in their Belgian Cup Round of 16 on Wednesday (December 21).The hosts won the competition in 2021 but couldn't retain the title last season, losing in the seventh round to arch-rivals Club Brugge. Genk beat Westerlo 1-0 in the previous round, thanks to a Paul Onuachu first-half winner. Anderlecht, meanwhile, made the final of the previous edition against Gent, losing 4-3 on penalties after a goalless 120 minutes.Both teams are playing their first competitive game since November. They met in the Belgian Pro League at Lotto Park, where goals from Onuachu and Gerardo Arteaga helped Genk to a 2-0 win.KRC Genk@KRCGenkofficialStaat 21 december al een tijdje in 't blauw in je agenda gearceerd? Check hier de belangrijk info voor 𝗞𝗥𝗖 𝗚𝗲𝗻𝗸 - 𝗥𝗦𝗖 𝗔𝗻𝗱𝗲𝗿𝗹𝗲𝗰𝗵𝘁 krcgenk.be/nl/nieuws/4920…111Staat 21 december al een tijdje in 't blauw in je agenda gearceerd? Check hier de belangrijk info voor 𝗞𝗥𝗖 𝗚𝗲𝗻𝗸 - 𝗥𝗦𝗖 𝗔𝗻𝗱𝗲𝗿𝗹𝗲𝗰𝗵𝘁 ⬇️krcgenk.be/nl/nieuws/4920…Genk vs Anderlecht Head-to-Head and Key NumbersThe two teams have crossed paths 85 times across competitions. Anderlecht lead 46-23, while 16 games have ended in draws.They have met five times in the Belgian Cup, with Anderlecht leading 3-2. Genk won 2-1 when they last met in the semifinal in the 2020-21 edition of the competition.Genk and Anderlecht have endured contrasting fortunes in the Belgian Pro League this season. The hosts are atop the standings with 46 points, while Anderlecht are in 11th place with 20 points.Genk have the best attacking and defensive record in the league, scoring 45 goals in 17 games and conceding 15 goals.$1000 No Sweat First Bet on FanDuelGenk vs Anderlecht PredictionGenk have been in tremendous form this season, riding an 11-game winning streak. They have scored 15 goals in their last four home games and will look to continue that momentum.RSC Anderlecht@rscanderlechtHighlights friendly. RSC Anderlecht - Raków Czestochowa: 1-1. 🟣 #ANDRCZ453Highlights friendly. RSC Anderlecht - Raków Czestochowa: 1-1. 🟣⚪ #ANDRCZ https://t.co/CJ0uP0krvwAnderlecht, meanwhile, have seen an uptick in their form in recent games, losing just once in their last six outings, with that defeat coming against Genk. Considering the same, Genk should eke out a narrow win.Prediction: Genk 2-1 AnderlechtRisk-Free Bet up to $1,000 on BetMGMGenk vs Anderlecht Betting TipsTip 1: Result - GenkTip 2: Goals - Over/Under 2.5 Goals - Over 2.5Tip 3: Genk to score first - YesTip 4: At least one goal to be scored in the second half