Wolfsburg are second in the Bundesliga table, tied with Bayern Munich on points but behind on goal difference. They have 13 points from five matches, with a record of four wins and one draw.
Wolfsburg are coming off a 1-1 draw against Eichtract Frankfurt. Sam Lammers opened the scoring for the visitors with a goal in the 38th minute, but Wout Weghorst equalized for the hosts at the 70th-minute mark.
Meanwhile, Hoffenheim have been winless in the league since the opening weekend and sit in 10th spot in the table. They played out a 0-0 draw against Arminia in their last league game.
Hoffenheim vs Wolfsburg Head-to-Head
Wolfsburg and Hoffenheim have played 27 matches against each other, with the former winning 13 of those encounters. Hoffenheim have seven wins in their head-to-head record, while seven matches have ended in draws.
The last match between the two German sides ended in a 2-1 win for Hoffenheim.
Wolfsburg form (all competitions): W-W-W-D-D
Hoffenheim form (all competitions): W-D-L-L-D
Hoffenheim vs Wolfsburg Team News
Ermin Bicakcic, Benjamin Hubner and Havard Nordtveit haven't featured in a single game this campaign and will be unavailable for the match against Wolfsburg.
Sebastian Rudy's participation is in doubt due to a back problem.
Injured: Ermin Bicakcic, Benjamin Hubner, Havard Nordtveit
Doubtful: Sebastian Rudy
Paulo Otavio, William, Xaver Schlager and Bartosz Bialek remain on the treatment table for Mark Van Bommel's side. Dodi Lukebakio is still recovering from a hip problem, with Lukas Nmecha expected to replace him in the starting lineup on Saturday.
Injured: Paulo Otavio, William, Xaver Schlager, Bartosz Bialek
Doubtful: Dodi Lukebakio
Hoffenheim vs Wolfsburg Predicted XI
Hoffenheim Probable XI (4-2-3-1): Oliver Baumann; David Raum, Chris Richards, Kevin Vogt, Stefan Posch; Florian Grillitsch, Denns Geiger; Jacob Bruun Larsen, Christoph Baumgartner, Andrej Kramaric; Georginio Rutter
Wolfsburg Predicted XI (4-2-3-1): Koen Casteels; Jerome Roussill, Maxence Lacroix, John Brooks, Ridle Baku; Maximilian Arnold, Joshua Guilavogui; Renato Steffen, Maximilian Philipp, Lukas Nmecha; Wout Weghorst
Hoffenheim vs Wolfsburg Prediction
Wolfsburg have been a juggernaut this season, and despite their recent blips and injury problems, remain favorites to win against Hoffenheim.
We predict that Wolfsburg will beat Hoffenheim with ease.
Prediction: Wolfsburg 2-0 Hoffenheim