Leaders Melbourne City entertain fifth-placed Sydney at the Melbourne Rectangular Stadium in the A-League on Saturday (February 25).The hosts suffered their first defeat in nine league games, losing 3-2 against local rivals Melbourne Victory despite Mathew Leckie's brace. Nonetheless, they have a seven-point lead over second-placed Central Coast Mariners.Sydney, meanwhile, saw their three-game winning run snapped in a 1-1 draw against Brisbane Roar at the weekend. Nikola Mileusnic scored for Brisbane in the 34th minute before substitute Alex Parsons equalised for Sydney deep into injury time.Isuzu UTE A-League@aleaguemenBring. It. On With the table as tight as it's ever been, EVERY match matters in the @IsuzuUTE A-League 🎟️ bit.ly/3HYvjpP#WeAreALeagues223Bring. It. On 🔥With the table as tight as it's ever been, EVERY match matters in the @IsuzuUTE A-League 👊🎟️ bit.ly/3HYvjpP#WeAreALeagues https://t.co/Acsth7fLNIMelbourne City vs Sydney Head-to-Head and Key NumbersThe two teams have crossed paths 38 times across competitions since 2010, with Sydney leading 15-13.Five of their last six meetings have produced over 2.5 goals.Sydney recorded their first win over Melbourne since 2020 in the reverse fixture at home in December, winning 2-1.Melbourne have won their last three home meetings against Sydney, scoring ten times and conceding thrice.Melbourne are unbeaten at home across competitions this season, scoring 13 goals in their last three games and conceding just four.Sydney have won their last two away games. Interestingly, five of their seven wins in the league this season have come on their travels.Melbourne have the best attacking and defensive record in the A-League this season, scoring 39 goals in 16 games and conceding 17.Melbourne City vs Sydney PredictionLast week, the hosts suffered their first defeat in the league since December but have enjoyed a prolific run at home recently, scoring 18 goals in five games and keeping three clean sheets. Melbourne have won their last three home games against the Sky Blues.Melbourne City FC@MelbourneCityWe'll be without a key member of the squad when we take on Sydney this Saturday Catch up on all the latest 🎟 melbc.it/tickets151We'll be without a key member of the squad when we take on Sydney this Saturday 😔Catch up on all the latest 👇🎟 melbc.it/ticketsSydney, meanwhile, have enjoyed an upturn in fortunes in recent games, riding a four-game unbeaten league run. However, considering their recent record against Melbourne, a win seems unlikely.City have enjoyed an unbeaten run at home and have won their last three home games against Sydney. The trend should continue.Prediction: Melbourne City 3-1 SydneyMelbourne City vs Sydney Betting TipsTip 1: Result - MelbourneTip 2: Goals - Over/Under 2.5 Goals - Over 2.5Tip 3: At least a goal to be scored in the first half - YesTip 4: Mathew Leckie to score or assist any time - Yes