Egyptian superstar Mohamed Salah missed a penalty in the first-half as Liverpool suffered a 1-0 defeat against Leicester City in the Premier League.Liverpool started the game six points behind league leaders Manchester City by virtue of playing a game less than Pep Guardiola's side. They had a golden opportunity to take the lead in the first half when Mohamed Salah was fouled in the box. However, the 29-year-old winger had his penalty saved in the 16th minute before heading the rebound onto the crossbar.The Reds were forced to rue their missed chances as Leicester City claimed all three points at the King Power Stadium. Ademola Lookman scored in the 59th minute to hand Liverpool their second league defeat of the campaign.Football fans online took to Twitter to react to the Reds dropping vital points in the Premier League title race. A certain section of fans claimed that Manchester City are now the favorites to defend their league title. Here are some of the best tweets:Jamie Vardy@vardy7What way to finish the year...proud of the lads 💙🦊⚽️ See you all in 2022 twitter.com/lcfc/status/14…Leicester City@LCFCThe Foxes sign off in 2021 with a massive win over Liverpool 🔵#LeiLiv4:38 AM · Dec 29, 20212883111The Foxes sign off in 2021 with a massive win over Liverpool 🔵#LeiLivWhat way to finish the year...proud of the lads 💙🦊⚽️ See you all in 2022 twitter.com/lcfc/status/14…James Pearce@JamesPearceLFCFT: Leicester 1 #LFC 0: That's a highly damaging defeat for Liverpool. Got exactly what they deserved. Miles off it, especially second half. Leicester missing nine players and playing for the 2nd time in just over 48hrs. So many basic errors from Klopp's side. So poor3:24 AM · Dec 29, 20213443324FT: Leicester 1 #LFC 0: That's a highly damaging defeat for Liverpool. Got exactly what they deserved. Miles off it, especially second half. Leicester missing nine players and playing for the 2nd time in just over 48hrs. So many basic errors from Klopp's side. So poorLewis@Iewis20@LFC One of Firmino, Mane or Salah need to go. We need a change man.3:23 AM · Dec 29, 20211061@LFC One of Firmino, Mane or Salah need to go. We need a change man.Papa🇿🇦@qurqurqo@LFC Title conceded. Congrats @ManCity. Maybe we should focus on the Carabao and the FA cup, so we don't go trophyless.3:24 AM · Dec 29, 2021712@LFC Title conceded. Congrats @ManCity. Maybe we should focus on the Carabao and the FA cup, so we don't go trophyless.BenchWarmers@BeWarmersCongratulations Manchester City on winning the 2021/22 Premier League title 👏🏆4:00 AM · Dec 29, 20211357Congratulations Manchester City on winning the 2021/22 Premier League title 👏🏆 https://t.co/uOnmoJZm3IDRacarys@Dr_KopiteIt's Manchester City's title to lose.8:08 AM · Dec 29, 2021It's Manchester City's title to lose.Yo Pierre@tk_churuKlopp booking Salah and Mane’s tickets to Afcon after this game3:09 AM · Dec 29, 20212437453Klopp booking Salah and Mane’s tickets to Afcon after this game https://t.co/4jSELx6YT7GOAL@goalMohamed Salah proving that he is human after all 😳2:13 AM · Dec 29, 20219425551Mohamed Salah proving that he is human after all 😳 https://t.co/Pp9mIxd136Meet Rajani @Rajani_Meeti wld have taken league cup loss over this shit show...3:09 AM · Dec 29, 2021i wld have taken league cup loss over this shit show...🍹@LFCSai76 points lead for City and our next game is against Chelsea yeah forget about the league season focus on Champions League and Carabao Cup7:08 AM · Dec 29, 2021106 points lead for City and our next game is against Chelsea yeah forget about the league season focus on Champions League and Carabao CupEvidence Bongwe@Evidence_Shongw@brfootball Now we wait for city to drop points3:34 AM · Dec 29, 20215@brfootball Now we wait for city to drop points❀ S ❀@VetteIista@brfootball so let me get this straight, finished Chelsea are level on points with best XI itw Liverpool? 😭😭😭😭3:27 AM · Dec 29, 2021661@brfootball so let me get this straight, finished Chelsea are level on points with best XI itw Liverpool? 😭😭😭😭Ashraff Rahman@AshraffRahman3Brendan Rodgers might have just cost Liverpool another title.8:14 AM · Dec 29, 20212Brendan Rodgers might have just cost Liverpool another title.In My Footballing Opinion@AcretionDisc@goal Mo Salah’s last 16 league penalties:✅ Huddersfield✅ Newcastle✅ Arsenal✅ Brighton✅ Arsenal✅ Spurs✅ West Ham✅ Leeds✅ Leeds✅ West Ham✅ Man City ✅ Fulham ✅ Man City ✅ Chelsea ✅ Aston Villa ❌ Leicester 2:29 AM · Dec 29, 2021551@goal Mo Salah’s last 16 league penalties:✅ Huddersfield✅ Newcastle✅ Arsenal✅ Brighton✅ Arsenal✅ Spurs✅ West Ham✅ Leeds✅ Leeds✅ West Ham✅ Man City ✅ Fulham ✅ Man City ✅ Chelsea ✅ Aston Villa ❌ Leicester https://t.co/peHlKCTcixAlfonso♨️@PrimealfonsooSalah missed a pen and an open goal but no one is going to talk about it because his name isn’t Timo Werner1:50 AM · Dec 29, 20211629163Salah missed a pen and an open goal but no one is going to talk about it because his name isn’t Timo WernerOrs💉@deoorsWhen Salah, Mane, Keita and Matip leave for AFCON Liverpool will walk alone.3:28 AM · Dec 29, 2021961289When Salah, Mane, Keita and Matip leave for AFCON Liverpool will walk alone.Anfield Edition@AnfieldEditionProbably our worst performance of the season this.3:04 AM · Dec 29, 20211561100Probably our worst performance of the season this.Marcello Coelho@MarcelloCoelho7@AnfieldEdition Really awful today, it’s time for Firmino start over Mane3:26 AM · Dec 29, 20211@AnfieldEdition Really awful today, it’s time for Firmino start over ManeMatt@KopMattMane’s decision making has been atrocious for a very long time!1:41 AM · Dec 29, 202129Mane’s decision making has been atrocious for a very long time!Conn@ConnCFCIf Chelsea players missed the chances Mane and Salah missed tonight you wouldn’t hear the end of it.3:40 AM · Dec 29, 20212180240If Chelsea players missed the chances Mane and Salah missed tonight you wouldn’t hear the end of it.-@AnfieldRd96• 6 points behind Man City. • An utter disgrace of a performance. • Salah had to score his penalty. • Mané’s miss was shocking. • Matip our standout player. • Absolutely fuming with that. • What a shit way to end 2021. Chelsea (A), next.3:24 AM · Dec 29, 20212174227• 6 points behind Man City. • An utter disgrace of a performance. • Salah had to score his penalty. • Mané’s miss was shocking. • Matip our standout player. • Absolutely fuming with that. • What a shit way to end 2021. Chelsea (A), next.Paddy Power@paddypowerSalah and Mane with a last-ditch attempt to not get picked for the AFCON with their performances tonight.3:28 AM · Dec 29, 202160950Salah and Mane with a last-ditch attempt to not get picked for the AFCON with their performances tonight.Lennon Veasey 🇿🇲@Foxyproxy13131A defence of Castagne, Amartey, Ndidi and Thomas just kept a clean sheet against Mane, Jota and Salah, unreal that3:28 AM · Dec 29, 202152848A defence of Castagne, Amartey, Ndidi and Thomas just kept a clean sheet against Mane, Jota and Salah, unreal thatMohammed Fuseini@MfFuseiniDaniel Amartey showed Jurgen Klopp why the Afcon is not a little tournament by preventing his best front three from scoring today.3:32 AM · Dec 29, 202113326Daniel Amartey showed Jurgen Klopp why the Afcon is not a little tournament by preventing his best front three from scoring today.chlo@chloehenryxNice of mo and sadio to prepare us for AFCON by not showing up tonight 🥲3:35 AM · Dec 29, 202112014Nice of mo and sadio to prepare us for AFCON by not showing up tonight 🥲Following Chelsea's recent run of poor form, Liverpool were the closest to challenging Manchester City for the Premier League title. However, the Reds dropped points and are now six points behind the league leaders.Klopp's side were incredibly wasteful in front of goal. Liverpool took 21 shots during the game out of which only four were on target. Kasper Schmeichel made some important saves, including one to keep Mohamed Salah's penalty out.Leicester, on the other hand, secured a much-needed win to move to ninth place in the Premier League. The Foxes suffered a 6-3 defeat at the hands of Manchester City at the weekend. It is worth noting that Leicester City lost to Liverpool a week ago in the quarter-finals of the Carabao Cup.Liverpool will take on fellow title-rivals Chelsea on 2 January at Stamford Bridge.Mohamed Salah and Sadio Mane will soon leave Liverpool to play in the Africa Cup of NationsLiverpool's title challenge could suffer another serious blow in the coming weeks. Mohamed Salah and Sadio Mane are set to leave to represent their respective national teams at the Africa Cup of Nations throughout January.The attacking duo are amongst the top three highest goalscorers for the Reds this season and will leave after Liverpool's game against Chelsea. Sadio Mane has scored nine goals this season while Salah is Liverpool's highest goalscorer. The 29-year-old winger has scored 22 goals in 25 appearances for the Reds across all competitions.Salah's departure will a huge loss for Liverpool. Jurgen Klopp's side have important games in January, including a two-legged Carabao Cup semi-final tie against Arsenal.Liverpool FC@LFCWe will face @Arsenal in the semi-finals of the @Carabao_Cup! 🏆3:45 AM · Dec 23, 2021191142438We will face @Arsenal in the semi-finals of the @Carabao_Cup! 🏆 https://t.co/ZjcdhHR8Oy