The Premier League returns to the fold with another round of matches this weekend as Antonio Conte's Tottenham Hotspur lock horns with local rivals Fulham in an important clash on Saturday.Tottenham Hotspur vs Fulham PreviewFulham are currently in seventh place in the Premier League standings and have exceeded expectations so far this season. The Cottagers edged Brighton & Hove Albion to a 2-1 victory in their previous game and will look to achieve a similar result this weekend.Tottenham Hotspur, on the other hand, are in third place in the league table at the moment and have been fairly impressive so far. The North London outfit played out a 1-1 draw against West Ham United this week and will need to take it up a notch in this fixture.Tottenham Hotspur vs Fulham Head-to-Head and Key NumbersTottenham Hotspur have a good record against Fulham and have won 52 out of the 100 matches played between the two teams, as opposed to Fulham's 18 victories.Tottenham Hotspur have won 11 of their last 13 matches against Fulham in the Premier League but did drop points in two home games during this run.Fulham have won only one of their last 12 away matches against Tottenham Hotspur in the Premier League, with their previous such victory coming in 2014.Tottenham Hotspur have won their last four Premier League London derbies played at home and are closing in on a run of six such victories achieved between 2009 and 2010.Of the 10 London clubs to have featured in the Premier League, Fulham have the lowest win rate in London derbies with only 26 victories in 140 matches.Antonio Conte's side is currently on a five-game winning streak at the Tottenham Hotspur Stadium - the longest winning streak by the team at this venue.Tottenham Hotspur vs Fulham PredictionTottenham Hotspur have a good squad at their disposal but were unable to bring their cutting edge to the fore against West Ham United this week. The likes of Harry Kane and Dejan Kulusevski are in impressive form at the moment and will look to make their mark in this fixture.Fulham Football Club@FulhamFCGame Management 101.How to see out a win. #FFC73241Game Management 101.How to see out a win. 👊#FFC https://t.co/FlDmdMs3f0Fulham can pack a punch on their day and have pulled off a few surprising results so far this season. Tottenham Hotspur are the better team at the moment and should be able to win this game.Prediction: Tottenham Hotspur 2-1 Fulham2 for 1 New Player Bonus at BarstoolTottenham Hotspur vs Fulham Betting TipsTip 1: Result - Tottenham HotspurTip 2: Game to have over 2.5 goals - YesTottenham Hotspur@SpursOfficialBack to work ahead of the weekend 3932161Back to work ahead of the weekend ✊ https://t.co/AUY6jCJO4pTip 3: Fulham to score first - YesTip 4: Harry Kane to score - Yes