Wanda Metropolitano was the venue when Spain hosted Argentina in the last round of international friendlies this term. Any doubts about it being a tight fixture where thrown into the dustbin at the end of the 90 minutes as Spain absolutely schooled Argentina, who were without the injured Lionel Messi.From the first minute, Spain was in complete control of the game as their deft passing and movement proved too much to handle for the Argentineans. Diego Costa scored the opening goal in the 12th minute, Thiago Alcantara and Iago Aspas also found the back of the net but the star of the night was Isco who capped off a brilliant performance with an incredible hat-trick. Otamendi's solitary goal in the 39th minute proved only to be a consolation.Here's how twitter reacted:Diego Costa's opener:Gol! Diego Costa doesn't miss and puts Spain 1-0 in front. #SPAARG pic.twitter.com/3qaMyO3ZVQ— Vincent (@VincentGuzman_) March 27, 2018Isco's third goal:Isco reads the passing lane then completes his hat-trick. Argentina blown away. pic.twitter.com/ZwSHAEWACd— Kiyan Sobhani (@KiyanSo) March 27, 2018Twitter erupts!Argentina's defenders are so bad it's untrue. They make John Stones look like Franco Baresi #SPAARG— SCHOLES (@iamscholes) March 27, 2018It's fair to say that @Argentina and @spain players have trouble understanding the concept of a friendly #SPAARG pic.twitter.com/8zGfUVF0jT— Hish H (@Hjsh4m) March 27, 2018*When Pique joins up with Messi back in Barca*"Is that your country??"#SPAARG pic.twitter.com/5FI3q3joyy— FootySays (@Footy_Says) March 27, 2018And ppl think Argentina will win the world cup 😂😂😂😂😂😂 banter team #SPAARG #WorldCup #Russia2018— TheGodFather (@AussieRyan23) March 27, 201845 mins: Spain 2-1 Argentina74 mins: Spain 6-1 Argentina#SPAARG pic.twitter.com/GGMwIV0Am9— 888sport (@888sport) March 27, 2018Not only does he stops them he creates them too David De Gea with an Assist for spain😛😎🙌⚽⚽ #SPAARG pic.twitter.com/eG6uNZe2JY— San T (@SantyMkhabela) March 27, 2018Argentina without Messi is useless!!!#SPAARG— Akinkuade Oluwadare Tobi (@Akinkuadedare19) March 27, 2018caballero be doing the mannequin challenge. #SPAARG 😏😏😂😂 pic.twitter.com/6FwuOrI2Yu— Bright_👑 (@brytex_7) March 27, 2018Spain 6-1 ArgentinaWhat the hell is going on?!#SPAARG #ESPARG pic.twitter.com/ne2qv0nDbc— 𝗪𝖆𝖑𝖈𝖔𝖙𝖙 (@JrMoe_) March 27, 2018There is nothing friendly about the end to #ESP v #ARG. Argentina have been humiliated and are putting in some horror tackles. Throw Sergio Ramos into the mix and it’s a nightmare for Anthony Taylor to referee… #SPAARG— Scott Hunt (@scotthunt92) March 27, 2018Isco-Disco!Isco: Is the first Real Madrid player to score a hat-trick for Spain since April 2003 (Fernando Morientes vs Ecuador)— WhoScored.com (@WhoScored) March 27, 2018Sergio Ramos showing his appreciation for Isco. 😘😂 pic.twitter.com/Pb80c9Beqy— Indy Football (@IndyFootball) March 27, 2018Magnificent from Isco. Waited a long time to be a true part of a Spain team and he’s at the centre of one now. As valuable as anyone.— David Cartlidge (@davidjaca) March 27, 2018Perfect substitution, ISCO off for Vazquez. Best performance from Isco this season, big, big days coming ahead. Champions League and the World Cup inbound, top 10 player in the world when on his day. ISCO ALARCON.— Iscoholic (@Iscoholic) March 27, 2018After watching Isco with La Roja pic.twitter.com/rCn4cnKePE— Ryan. (@Rygista) March 27, 2018Isco is beautiful. When he’s in form, he steals the spotlight from everyone else, and this is all I want to see honestly.— Jenna Chami (@JennaChami) March 27, 2018Isco is the first Spanish National Team player to score a hat-trick against a nation who has won the World Cup (Argentina)! 🔥[@2010MisterChip] pic.twitter.com/UdBlEinpZd— SB (@Realmadridplace) March 27, 2018