Is pyrrole disorder linked to your mental health condition? Learn more about this complex condition

What you feel today may have an underlying cause such as pyrrole disorder. (Image via Pexels/ RDNE Stock)
What you feel today may have an underlying cause such as pyrrole disorder. (Image via Pexels/ RDNE Stock)

Pyrrole disorder or pyroluria, is a clinical condition that is characterized by an excess of pyrrole molecules. These molecules are directly associated with mood regulation. This dysfunction may lead to a significant disruption in the emotional landscape of an individual. Your physical health is constantly interacting with your mental health.

This disorder creates deficiencies of essential nutrients such as Zinc and Vitamin C. Hence, they are potentially linked to mood disorders such as bipolar disorder. It is a condition that isn’t that well-known in mainstream medicine, but doctors and mental health professionals are seeing more and more of it in clinical practice.

Unfortunately, there is less awareness and understanding of this complex condition and how it continually impacts many individuals.

Any issues in biochemistry can lead to difficulties in our mental health. (Image via Vecteezy/Kseniia Chunaeva)
Any issues in biochemistry can lead to difficulties in our mental health. (Image via Vecteezy/Kseniia Chunaeva)

What is pyrrole disorder? What are the common pyroluria symptoms?

When we talk about the role of nature in mental health conditions, we cannot miss out on this disorder. (Image via Cottonbro Studio)
When we talk about the role of nature in mental health conditions, we cannot miss out on this disorder. (Image via Cottonbro Studio)

Pyrrole disorder is an imbalance in the body that affects the synthesis of hemoglobin. It causes the body to overproduce a substance called HPL.

This disorder can cause a deficiency in hormones that are often associated with making us feel better and happier. The most common hormones include serotonin, the happy hormone dopamine, and GABA. We often see pyrrole disorder linked to conditions such as anxiety, OCD, ADHD, and many mental health conditions.

Additionally, we must also consider the detrimental effects of heavy metals and toxins, which can disrupt brain function, leading to cognitive dysfunction and mood alterations. Other common symptoms of this condition include feeling irritable, an inability to self-regulate emotions, rage and fits of anger, and sensitivity.


What causes pyrrole disorder?

What causes this disorder? and can it transmit within families? (Image via Vecteezy/ 890826026346)
What causes this disorder? and can it transmit within families? (Image via Vecteezy/ 890826026346)

The role of nature and nurture in the development of a condition can't be missed. However, pyroluria is most likely attributed to genetic components. Yes, this may run in the family and you may be most vulnerable if there is a history of mood disorders in your family.

While you may have the predisposing gene, you don't need to develop the condition. However, severe emotional or physical trauma frequently causes the onset of pyroluria. We often underplay the role of traumatic experiences in the development of physical health conditions, but remember that your body also undergoes various internal changes.

Additionally, a poor diet that lacks these nutrients and constant exposure to toxins may contribute to the development of this condition.


What is recommended as a pyroluria treatment?

What is recommended as a treatment for this disorder? (Image via Vecteezy/Ditta Karmawan)
What is recommended as a treatment for this disorder? (Image via Vecteezy/Ditta Karmawan)

An integrated approach is likely to work best when you receive a diagnosis of pyrrole disorder. This means that you will have to work simultaneously on your physical and mental health. An integrated practitioner can help you get started on a diet that helps you recover from your deficiencies.

However, therapy may vary depending on your condition. For instance, if you are displaying the symptoms of bipolar disorder, the treatment is likely to be different from the symptoms of ADHD. You may have to work on actively making changes to your lifestyle to recover from this condition.


While a general practitioner can help you identify a diagnosis, it may be based on the symptoms you are presenting. Working with an integrative therapist offers an opportunity to see any underlying concerns or conditions that may be affecting your health. If you do see the symptoms of pyrrole disorder, remember that there is a treatment that can prevent you from feeling less vulnerable and troubled.


Janvi Kapur is a counselor with a Master's degree in applied psychology with a specialization in clinical psychology.

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