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The New England Patriots rebounded last week with a resounding victory over AFC East rival New York Jets.
The Indianapolis Colts blew a late lead and eventually the game to a Washington franchise led by Taylor Heinicke.
The Colts need a win in the worst way, but traveling to Foxboro and pulling off the upset of the resilient Patriots will be a challenge.
Today we look at the best DFS plays from this intriguing match-up.
Best quarterback picks
Cash Games and Tournaments: Sam Ehlinger, QB, Indianapolis Colts (DraftKings $5K, FanDuel $6.3K)
The New England Patriots want to ground and pound their opposition into submission. The Patriots deploy a run-heavy-based approach that rarely will they ask their QB to do anything.
At least we have seen a glimpse of upside from Indianapolis QB Sam Ehlinger, who is more athletic than you think and can be an asset on the ground using his legs.
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Best running back picks
Cash Games: Deon Jackson, RB, Indianapolis Colts (DraftKings $5.2, FanDuel $5K)
With the trade of Nyheim Hines, and the injury to Jonathan Taylor, Deon Jackson should have even more opportunities in the Colts' backfield to establish himself as a pass-catcher. Jackson appears to be the next man up in the Colts' backfield.
Tournament: Rhamondre Stevenson, RB, New England Patriots (DraftKings $6.2K, FanDuel $8K)
Rhamondre Stevenson has been nothing short of sensational. Stevenson has taken over the Patriots' backfield, earning the most important touches as a receiver and around the goal line.
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Wide receivers and tight ends
Cash game: Michael Pittman Jr., WR, Indianapolis Colts (DraftKings $6.8K, FanDuel $6.4K)
Michael Pittman Jr. is far and away the most talented receiver in this game. Pittman Jr. will receive even more targets now that the Colts traded Hines to Buffalo.
Tournament: Jakobi Meyers, WR, New England Patriots (DraftKings $5.4K, FanDuel $6.8K)
Jakobi Meyers is one of the most underrated receivers in the NFL. Meyers continues to produce week in and week out. The Patriots remain focused on the run game, but when they air it out, they are looking for Meyers to move the chains.
Jakobi has earned the trust of the coaching staff QB Mac Jones, and he should earn your trust for your DFS lineup.
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