San Francisco 49ers vs Los Angeles Rams NFL Odds, Line, Pick, Prediction, and Preview: October 30 | 2022 NFL Season

Los Angeles Rams v San Francisco 49ers
Los Angeles to host San Francisco on Sunday

The San Francisco 49ers will take on the Los Angeles Rams in week eight of the NFL on Sunday (October 30) at the SoFi Stadium.

The 49ers, on a two-game losing streak, are third in the National Football Conference (West). They will look to snap that run against the Rams who have swapped places with the 49ers for second spot.


San Francisco 49ers vs Los Angeles Rams: Betting Odds

TeamMoneylineSpreadOver/Under
San Francisco 49ers-115-1 (-110)O 42 (-110)
Los Angeles Rams-105+1 (-110)U 42 (-110)

San Francisco's new season started with an away loss to the Chicago Bears (19-10). The 49ers put on a great offensive display in their next two games, beating the Rams (24-9) and the Carolina Panthers (37-15).

Their two-game win streak ended against the Atlanta Falcons in a one-sided affair (28-14). Their latest outing was against the mighty Kansas City Chiefs, who were dominant against the California team. Kansas' offense was too strong to handle for the 49ers as they succumbed to a 44-23 defeat.

The Rams, meanwhile, have won and lost three wins apiece this season. They opened their season with a 31-10 loss to the Bills. They back strong in Week 2 to beat the Falcons 31-27 before beating the Arizona Cardinals 20-12.

The Rams lost their next outing 24-9 to the 49ers before losing to the Dallas Cowboys (22-10). They won their last outing against the Carolina Panthers (24-10).


San Francisco 49ers vs Los Angeles Rams: Match Details

Fixture: San Francisco 49ers @ Los Angeles Rams

Date & Time: Sunday, October 30; 04:25 pm EDT

Venue: SoFi Stadium, Los Angeles, California


San Francisco 49ers vs Los Angeles Rams: Key Stats

The Rams have won only three of their last ten games against the 49ers. They lost against them this season in Week 4. Los Angeles is averaging only 17.3 points per game while conceding 21.0 and has 11 TDs. San Francisco, meanwhile, is averaging 20.3 ppg and is conceding 19.0 but has 17 TDs.


San Francisco 49ers vs Los Angeles Rams: Pick

Darrell Henderson has been consistent with an inconsistent Rams team. The 25-year-old running back seems to be growing with every performance. In six games, Darrell has 181 rushing yards, averaging 30.2 rushing yards per game along with two TDs. He could be a great asset for Los Angeles on Sunday.

Pick: Darrell Henderson Total Rushing Yards Over 41.5 (-115)


49ers vs Rams: Prediction

The Los Angeles Rams will look to take revenge for their Week 4 loss against the San Francisco 49ers. However, this time Los Angeles is playing at home, which will be a slight advantage. Their two-game losing streak might affect the way the 49ers would approach the game. Expect the Rams to win this one.

Prediction: 1st Half Total Under 20.5 (-115)

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