Thursday Night Football: 49ers vs. Seahawks - Odds, Lines, Picks, and Predictions | Week 15 

Carolina Panthers v Seattle Seahawks
Geno Smith threw for 264 yards in last week's loss against the Panthers.

The San Fransisco 49ers head north to Seattle to take on the Seahawks and open up Week 15.

Seattle was looking at this spot in the schedule and hoped they would be playing for first place in the NFC West, but due to an untimely loss against the Carolina Panthers last week, they now find themselves two games behind San Fransisco.

After back-to-back stellar performances from Brock Purdy, the 49ers' Super Bowl hopes remain alive. After finding their groove late in the season and making a first-place push, it seemed like all that would be lost after Jimmy Garapplo sustained an injury on the first drive of the game against Miami in Week 13.

However, with the emergence of the next great quarterback in the NFL, San Francisco is now as confident as others


49ers vs. Seahawks Betting Odds

SpreadMoneylineOver/Under
49ers-3.5 (-110)-190Over 43 (-110)
Seahawks+3.5 (-110)+160Under 43 (-110)


49ers vs. Seahawks Match Details

Fixture: San Fransisco 49ers @ Seattle Seahawks

Date and Time: Thursday, December 14, 8:15 p.m. EST

Venue: Lumen Field, Seattle, Washington


49ers vs. Seahawks Best Picks

The under has been a great play all year in Thursday Night Football; it's almost to the point where bettors should take the wager without even seeing the line.

Looking at the numbers, though, it's still a smart play. This game will go one of two ways. Either San Francisco's defense holds it down like they have all season and keeps Seattle to 20 points or less, or Brock Purdy comes down to earth, has a terrible game, and Seattle picks up a win with a low total score.

Under 43 (-110)

49ers vs. Seahawks Predictions

Seattle has been the biggest surprise of the season thus far. The Geno Smith lead team was predicted to be the worst in the league, but Pete Carol has proven to be a far better coach than anyone realized, taking this seemingly dusty QB and making him a star.

Seeing Seattle at home as an underdog is always an enticing bet. This game will come down to Brock Purdy's performance, as bettors will have to see if he can string together another magical game. Win or lose, it'll be close. Seattle with the points is the smart play here.

Seattle +3.5 (-110)

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