Cardinals vs Rangers: Game 2 prediction, odds, injuries, and picks

The St. Louis Cardinals and Texas Rangers are set to square off on Saturday for Game 2 of their interleague series. The Rangers wasted little time blowing out the Cardinals in the series opener, and St. Louis has to find a way to respond.

It's been a great start to the season for the Cardinals in 2025, as they are 32-25 on the year. Texas is still trying to get things turned around, sitting at 28-30 on the year.

The odds for Game 2 of the series are now out, and some predictions can be made.

Cardinals vs. Rangers prediction

Sonny Gray is pitching today - Source: Imagn

Veteran Sonny Gray is set to start for the St. Louis Cardinals on Saturday. He has gone 5-1 with a 4.06 ERA so far in 2025. Pitching has been carrying the Cardinals to begin the year, and Gray should keep that trend going.

Lars Nootbar leads the Cardinals with eight home runs, while Brendan Donovan is hitting .333. St. Louis continues to come up with clutch hits, which will be something to watch in this matchup.

The Texas Rangers will send veteran Patrick Corbin to the mound on Saturday, and he is 3-3 with a 3.75 ERA. Corbin needs to set the tone for the Rangers in this game as they don't have a ton of offense.

Wyatt Langford has belted 11 home runs for Texas, but this team needs more offense. Look for the Rangers to come up just a bit short in this one as Gray can get the win.

Prediction: St. Louis Cardinals 4, Texas Rangers 3

Cardinals vs. Rangers odds

Money Line: St. Louis Cardinals -155, Texas Rangers +130

Run Spread: Cardinals -1.5 (+115), Rangers +1.5 (-135)

Total Runs: Over 7.5 (-130), Under 7.5 (+110)

Cardinals vs. Rangers injuries

St. Louis Cardinals injury report

Brendan Donovan (2B): Day to day (Left hip tightness)

Zack Thompson (LHP): 60-Day IL (Left lat strain)

Texas Rangers injury report

Nathan Eovaldi (RHP): Day to day (Triceps fatigue)

Evan Carter (OF): 10-Day IL (Right quad strain)

Cody Bradford (LHP): 15-Day IL (Left elbow sprain)

Joc Pederson (DH): 10-Day IL (Right hand fracture)

Kumar Rocker (RHP): 15-Day IL (Right shoulder impingement)

Cardinals vs. Rangers picks

The St. Louis Cardinals will respond with a big win on Saturday, so when making picks, focus on the visitors.

Money Line: St. Louis Cardinals -155

Run Spread: Texas Rangers +1.5 (-135)

Total Runs: Under 7.5 (+110)

About the author

Ryan Burks is a baseball journalist at Sportskeeda with over 7 years of experience in the field, writing for publications such as Knup Sports. Ryan graduated from Elmhurst College in 2009 with a degree in Communications.

Ryan is a huge Chicago Cubs fan and enjoys their storied history and traditions. His favorite sporting moment was when the Cubs won the 2016 World Series, breaking a championship drought that dated back to 1908.

His favorite player was Ken Griffey Jr., as Ryan grew up during his prime and he was the coolest player in league history. Greg Maddux also deserves a mention, as he was truly amazing on the mound.

When not working or watching sports, Ryan coaches basketball and baseball, loves fishing, and spends time with his family.

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Edited by Neha

Cardinals vs Rangers: Game 2 prediction, odds, injuries, and picks - May 31, 2025