Cubs vs Phillies: Game 2 prediction, odds, injuries, and picks

The Cubs are looking to bounce back from a narrow loss at the hands of the Phillies, Monday night. Chicago were outgunned by the Phils in Game 1 that went to 11 innings and only concluded after Brandon Marsh's walk-off single drove in J.T. Realmuto.

Kyle Tucker opened the scoring tab in the very first inning for his 13th homer of the season. However, heroics from Nick Castellanos and undrafted third baseman Otto Kemp saved the hosts from their seemingly unending downfall in the absence of Bryce Harper.

Cubs vs. Phillies recent form and records

The Cubbies' record now stands at 40-26 after suffering back-to-back defeats. Nevertheless, they still hold the lead in the NL Central lead by four games over the Cardinals.

The Phillies, meanwhile, have put a momentary stop from their free fall in the past few weeks. Before their narrow win in extras, Philly lost five-straight games — including a humiliating sweep at the hands of the lowly Pirates.

Cubs vs.Phillies odds

Money Line: CHC (-110), PHI (-110)

Run Spread: CHC -1.5 (+145), PHI +1.5 (-182)

Total Runs: O 9.5 (-106), U 9.5 (-114)

Cubs vs. Phillies injuries

CHC injury report

Shota Imanaga (SP): 15-day IL (hamstring)
Miguel Amaya (C): 10-day IL (oblique)
Javier Assad (SP): 60-day IL (oblique)
Eli Morgan (RP): 60-day IL (elbow)
Justin Steele (SP): 60-day IL (elbow)
Porter Hodge (RP): 15-day IL (oblique, hip)

PHI injury report

Aaron Nola (SP): 15-day IL (ankle)
Bryce Harper (1B): 10-day IL (wrist)

Cubs vs. Phillies projected lineup

CHC projected lineup

Ian Happ (LF)
Kyle Tucker (RF)
Seiya Suzuki (DH)
Pete Crow-Armstrong (CF)
Carson Kelly (C)
Michael Busch (1B)
Dansby Swanson (SS)
Nico Hoerner (2B)
Matt Shaw (3B)
Colin Rea (SP, 4-2 | 3.59 ERA | 43 K)

PHI projected lineup

Bryson Stott (2B)
Trea Turner (SS)
Kyle Schwarber (DH)
Alec Bohm (1B)
Nick Castellanos (RF)
Max Kepler (LF)
J.T. Realmuto (C)
Otto Kem (3B)
Brandon Marsh (CF)
Mick Abel (SP, 1-0 | 0.79 ERA | 11 K)

Cubs vs. Phillies picks and game prediction

Veteran pitcher Colin Rea's job has already been cut out for him as neophyte hurler Mick Abel will take the bump for the Phillies. The former lottery pick has impressed in two starts this year with a 0.79 ERA across 11 1/3 innings. Odds-wise, the game is predicted to sway on either side's favor.

Run Line: PHI +1.5 (-182)

Total Runs: U 9.5 (-106)

Prediction: PHI wins, 4-3

About the author

Daniel Santiago is a journalist who has been reporting on baseball at Sportskeeda since 2022. He was drawn towards the sport after the underlying statistics and the analysis surrounding it grabbed his attention.

Daniel particularly enjoys furnishing reports about historic events in baseball and analyzing the game through a statistic-based outlook, based on Fangraphs and Baseball-Reference. This is in line with how he enjoyed watching baseball as a pastime. As a writer, he is very particular about cross-checking from reputable sources and doing his due diligence.

He became a lifelong Hideki Matsui fan after his exploits in the 2009 World Series for the New York Yankees. Among the current generation, Daniel's favorites include Shohei Ohtani and Jung Hoo Lee. Daniel is a huge follower of Asian baseball and both Ohtani and Lee have been in the top echelon of their respective leagues during their time with the NPB and KBO.

His favorite moment as a baseball fan was the final at-bat of the 2023 World Baseball Classic between Shohei Ohtani and Mike Trout. He believes there aren't many words to fittingly describe the intensity of the moment.

As an avid sports fan, Daniel watches other sports and Esports when not writing about baseball.

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Edited by Daniel Santiago

Cubs vs Phillies: Game 2 prediction, odds, injuries, and picks - June 10, 2025