The Chicago Cubs travel to the Motor City for a high-stakes, three-game series against the Detroit Tigers. Both squads have had amazing starts to the 2025 campaign, with Chicago being five games ahead in the NL Central standings while Detroit currently holds the best record in MLB.
Game 1 will feature reigning AL Cy Young winner Tarik Skubal squaring off against a tenacious Cubs offense that is fourth-best across the majors with a .780 OPS. In addition, Chicago came away with the series victory the last time the two teams met in August 2024.
Cubs vs. Tigers recent form and records

The Cubbies are heading into the contest having won eight of their last 10 games. They now possess a 39-23 record and a superb 19-12 tally on the road. The squad is steadily rising in the conversations of National League pennant winners this year as they lead all of MLB in run differential at an astonishing +106.
The Tigers, on the other hand, were the first team to reach 40 wins this year, as their record stands at 41-23. They've also posted one of the best win-loss tallies at home at 21-7. However, they're heading into the series against the Cubbies on the back of a surprising series loss to divisional opponent the Chicago White Sox.
Cubs vs. Tigers odds
Money Line: CHC (+168), DET (-189)
Run Spread: CHC +1.5 (-139), DET -1.5 (+115)
Total Runs: O 7.5 (+111), U 7.5 (-134)
Cubs vs. Tigers injuries
CHC injury report
- Shota Imanaga (SP): 15-day IL (hamstring)
- Miguel Amaya (C): 10-day IL (oblique)
- Javier Assad (SP): 60-day IL (oblique)
- Eli Morgan (RP): 60-day IL (elbow)
- Justin Steele (SP): 60-day IL (elbow)
- Porter Hodge (RP): 15-day IL (oblique, hip)
DET injury report
- Reese Olson (SP): 15-day IL (finger)
- Alex Cobb (SP): 15-day IL (hip)
- Jackson Jobe (SP): 15-day IL (flexor)
- Matt Vierling (CF): 10-day IL (shoulder)
- Jose Urquidy (SP): 60-day IL (elbow)
- ALex Lange (SP): 60-day IL (lat)
- Ty Madden (SP): 60-day IL (shoulder)
Cubs vs. Tigers projected lineup
CHC projected lineup
- Ian Happ (LF)
- Kyle Tucker (RF)
- Seiya Suzuki (DH)
- Carson Kelly (C)
- Dansby Swanson (SS)
- Pete Crow-Armstrong (CF)
- Nico Hoerner (2B)
- Justin Turner (1B)
- Matt Shaw (3B)
- Ben Brown (SP, 3-3 | 5.72 ERA | 71 K)
DET projected lineup
- Parker Meadows (CF)
- Gleyber Torres (2B)
- Kerry Carpenter (RF)
- Riley Greence (LF)
- Spencer Torkelson (1B)
- Colt Keith (DH)
- Dillion Dingler (C)
- Zack McKinstry (3B)
- Trey Sweeney (SS)
- Tarik Skubal (SP, 5-2 | 2.26 ERA | 99 K)
Cubs vs. Tigers picks and game prediction
The Northsiders have won seven consecutive series since May 12, heading into Game 1. However, bookmakers have them as the underdogs even though the Tigers recently lost a series to the White Sox, thanks to Tarik Skubal, who will be taking the bump today. It should be a close game all around and will boil down to the visitors' attempt at stifling the AL Cy Young awardee.
Run Line: CHC +1.5 (-139)
Total Runs: U 7.5 (-134)
Prediction: DET wins, 3-2