Mariners vs. Blue Jays: Game 1 prediction, injuries, odds, bets, and picks - October 12, 2025 | ALCS Series

Seattle delivered in a 15-inning ALDS epic and now now opens the ALCS against a Toronto squad that caught fire late in the regular season and features multiple high-impact bats.

The series is set up as an interesting mismatch: Seattle brings a power chase and a fresh bullpen after an exhausting Game 5; Toronto features depth for its rotation and veteran postseason savvy. Managerial choice and bullpen usage will be critical from the first pitch.

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Starting Pitchers

Bryce Miller - Seattle Mariners

Miller has had an up-and-down 2025; his profile is a heavy fastball with swing-and-miss upside when the heater and breaking ball are both working; when he misses his spots, hard contact follows.

In a Game 1 ALCS spot, he’s a live arm, high ceiling if he pounds the zone and keeps the pitch count low, but also a higher bust risk that the Blue Jays will try to exploit early.

Kevin Gausman - Toronto Blue Jays

Gausman brings reliable postseason experience and a 2025 line that reflects his track record: on the season, he logged an above-average strikeout rate and controlled damage.

He excels by changing tunnel and elevation and can dominate when his fastball and splitter/slider are in sync. Toronto will look to get length and let its bullpen protect late leads if Gausman can avoid a multi-run inning.

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Hot Hitters

Seattle Mariners

Josh Naylor - clutch bat and run producer with the ability to drive in key RBI; a threat in the middle of Seattle’s lineup.

Cal Raleigh - a one-swing game-changer; his power from the catcher spot forces pitchers to attack carefully.

Toronto Blue Jays

Vladimir Guerrero Jr. - middle-of-order power and run production; a mistake pitch to Vlad is rarely forgiven.

George Springer - veteran postseason performer (status permitting) who raises the ceiling for Toronto’s lineup in big spots.

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Injury Report

Blue Jays:

• Jose Berrios – 15-Day IL (elbow)
• Ty France – 10-Day IL (oblique)
• Chris Bassitt – 15-Day IL (back)
• Bo Bichette – 10-Day IL (knee)
• Robinson Pina – 60-Day IL (elbow)
• Nick Sandlin – 60-Day IL (elbow)
• Yimi Garcia – 60-Day IL (ankle)
• Bowden Francis – 60-Day IL (shoulder)
• Ryan Burr – 60-Day IL (shoulder)
• Angel Bastardo – 60-Day IL (elbow)

Mariners:

• Bryan Woo – day-to-day (pectoral)
• Jackson Kowar – 15-Day IL (shoulder)
• Trent Thornton – 60-Day IL (achilles)
• Gregory Santos – 60-Day IL (knee)
• Ryan Bliss – 60-Day IL (biceps)

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Current Odds

Run Line:

• Mariners +1.5 (−148)
• Blue Jays −1.5 (+129)

Total:

• Over 8 (−103)
• Under 8 (−118)

Moneyline:

• Mariners +141
• Blue Jays −174

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Best Bets & Final Prediction

1. Blue Jays Moneyline (−174)
2. Total Under 8 (−118)
3. Vladimir Guerrero Jr. Total Bases 2+ (-103)

Final score prediction: Blue Jays 5, Mariners 2