Mets vs. Angels: Game 1 prediction, lineup, odds, injuries and picks

The New York Mets are in an intense battle with the Philadelphia Phillies in the National League East. The Mets cut down the Phillies' division lead to 0.5 games after a 3-2 win against the Cincinnati Reds in their last outing.

The Los Angeles Angels are coming into Monday's series opener on the back of a morale-boosting series win over the Mets' division rivals, the Phillies, over the weekend.

Mets vs. Angels prediction

Although the Mets dropped their previous series, they will be upbeat after a win against the Reds in the series finale to avoid a sweep. The Mets will have a significant advantage from the mound on Wednesday as Kodai Senga will take the ball for New York.

Senga boasts a league-best 1.39 ERA with a 7-3 record. The Mets ace had a scoreless outing in his last start, allowing four hits with four strikeouts. The Mets' offense will fancy its chances against Tyler Anderson.

Anderson is 2-6 with a 4.34 ERA this season. In his last start for the Angels, Anderson was picked for four earned runs in five innings.

Prediction: New York Mets 4, Los Angeles Angels 1

Odds

Money Line: Mets (-189), Angels (+156)

Run Line: Mets (+112), Angels (-134)

Total Runs: Over 9 (+100), Under 9 (-120)

Injury report

Mets

Starling Marte: 10 Day IL (Knee)

Jesse Winker: 10 Day IL (Back)

Max Kranick: 15 Day IL (Elbow)

Jose Butto: 15 Day IL (Illness)

Dedniel Nunez: 15 Day IL (Elbow)

Paul Blackburn: 15 Day IL (Shoulder)

Pete Alonso: day-to-day (Hand)

Angels

Christian Moore: 10 Day IL (Thumb)

Chris Taylor: 10 Day IL (Hand)

Robert Stephenson: 15 Day IL (Biceps)

Anthony Rendón: 60 Day IL (Hip)

Ben Joyce: 60 Day IL (Shoulder)

Hunter Strickland: 60 Day IL (Shoulder)

Nolan Schanuel: day-to-day (Wrist)

Expert's picks

Despite a few mixed results in the last few weeks, betting on the Mets' defense with Kodai Senga on the mound is a reliable bet. With Pete Alonso likely to get back in the starting lineup on Monday, expect the Mets offense to pull through for Senga.

Money Line: New York Mets (+112)

Total Runs: Under 9 (-120)

About the author

Chaitanya Prakash is an editor who covers US Sports at Sportskeeda. His first brush with sportswriting was in 2012 when the greatest football manager of all time, Sir Alex Ferguson, bid farewell to the beautiful game.

Although having started out professionally as a cricket writer in 2022, Chaitanya's curiosity and indiscriminate interest in all sports in general eventually introduced him to America's favorite pastime.

While Chaitanya's favorite player from the current crop is the dynamic Venezuelan Ronald Acuna Jr., his all-time favorite, however, is Pedro Martinez, for his self-belief and consistency. He also rates Jose Bautista's iconic bat flip in 2015 as his favorite moment in baseball history.

Chaitanya specializes in reporting on technical aspects of the game or analyzing patterns behind specific plays. He also likes pondering over players' self-assessments following the conclusion of a game as it helps him get an idea of how they think about the sport in general.

When not cheering for his favorites across sports, Chaitanya likes being transported to the past through a good war documentary or a historical documentary in general.

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Edited by Chaitanya Prakash

Mets vs. Angels: Game 1 prediction, lineup, odds, injuries and picks - July 21, 2025