On Friday, all thirty MLB teams will be in action as yet another weekend kicks off. Although all teams will be hoping to score runs, some teams are lucky enough to feature stars who make a habit of smoking home runs.
Today, we will be examining the MLB players with the best probabilities of going deep on July 5, according to DraftKings Sportsbook. If you want to potentially win big, keep reading.
MLB Home Run Prop Bets July 5

Anthony Santander +330
The 22 home runs launched by Anthony Santander this season puts the Baltimore Orioles outfielder on pace to surpass his 2022 career-high figure of 33. A .304 hitter over his past seven games, the Venezuelan and his club will square off against the Athletics in Oakland on Friday.
Bobby Witt Jr. +340
Kansas City Royals shortstop Bobby Witt Jr. continues to astound fans. Currently the MLB leader in hits and doubles, the Texan boasts a 1.409 OPS since the start of July. On Friday, Witt will bring his .319/.369/.556 slashline to play against the Colorado Rockies.
The game is at Coors Field, which is one of the most home run-conducive parks in MLB. Additionally, in just 6 career games against the Rockies, Witt Jr. has hit .304 with a pair of homers and four RBIs.
"Bobby Witt Jr. - Kansas City Royals (14)" - MLB HR Videos
Brandon Lowe +390
Brandon Lowe connected for a solo shot on Thursday to help his Tampa Bay Rays win 10-8 over the Royals and complete the series sweep. In fact, three of Lowe's eight home runs this season have come over the past four games. Tonight, Lowe will look to continue his streak of good fortune against pitcher Michael Lorenzen of the Texas Rangers.
Yordan Alvarez +350
Yordan Alvarez almost singlehandedly did away with the Blue Jays in the Astros' recent series in Toronto. Over the course of four games, the big Cuban went 5-for-11, mashing two doubles, three home runs, and five RBIs.
Now, Alvarez and company will head to Minnesota to take on the Twins for a weekend set. Throughout 22 career games against Minnesota, Alvarez has hit .298 with 8 home runs.
"Out in a flash off the bat of Yordan Alvarez." - MLB
Shohei Ohtani +215
Shohei Ohtani has the best odds to hit a home run tonight, as his Dodgers begin a home set with the Milwaukee Brewers. With Friday being the superstar's 30th birthday, perhaps fans can expect even more magic than usual from the reigning AL MVP.
"114.2 MPH, 433 feet. Shohei Ohtani CLOBBERED that ball!" - Foul Territory
Although he has not homered since June 29, Ohtani's seven home runs over the past 15 days lead MLB over that period of time. At +215 odds, one could do far worse than to bet on the birthday boy.
Note: Odds are subject to change