The Boston Red Sox will look to secure back-to-back series wins Wednesday at Rogers Centre, following a dominant 10-2 victory over the Toronto Blue Jays in Tuesday's opener.Lucas Giolito is set to make his long-awaited return, taking the mound for his first start since October 2023. Toronto appears to be going with a bullpen game regardless of this being Jose Berrios' turn in the rotation.Red Sox vs. Blue Jays recent form and recordsBostonThe Red Sox appear to have flipped the switch. Alex Cora's troops hit five home runs in the series opener with the Blue Jays, extending the team's current win streak to three games.At 17-14 overall, Boston sits $44 in the red for MLB bettors and trails the New York Yankees by 1.5 games in the AL East pennant chase. However, it sits a game over .500 on the road where its 9-8 record has produced a modest $12 return on investment.TorontoThe Blue Jays are in the midst of their worst stretch of the season, tallying one win in their last nine games to plummet in the AL East standings. Now three games under .500 overall, the team sits 4.5 games out of first place.The fall from grace finds John Schneider on the verge of being fired with his team $263 in the red for MLB bettors. On the bright side, Toronto is $76 in the black at home, where it's won eight of 14 overall games.InjuriesBostonConnor Wong C 10 Day IL - HandMasataka Yoshida LF 10 Day IL - ShoulderRichard Fitts SP 15 Day IL - PectoralKutter Crawford SP 15 Day IL - KneeChris Murphy RP 60 Day IL - ElbowZach Penrod SP 60 Day IL - ElbowPatrick Sandoval SP 60 Day IL - ElbowTorontoNick Sandlin RP 15 Day IL - BackMax Scherzer SP 15 Day IL - LatErik Swanson RP 15 Day IL - HandAlek Manoah SP 60 Day IL - ElbowRyan Burr RP 60 Day IL - ShoulderAngel Bastardo SP 60 Day IL - ElbowStarting PitchersLucas Giolito (8-15, 4.88 ERA in 2023)Allowed 169 hits (41 HR) & 100 ER with a 204:73 K/BB ratio in 33 2023 starts.2-3 with a 5.40 ERA & 41:11 K/BB ratio in 43.1 career IP thrown vs. the Blue Jays.Must-Watch HittersBostonWith Boston's offense erupting for 30 runs in its last three games, there are a myriad of bats to look into when looking to attack player props in the second game of this series.Rafael Devers is on a tear, hitting safely in five straight games with home runs launched in four consecutive outings. He's +475 to keep the streak alive tonight.TorontoSelecting a hot Toronto bat has been tough—since plating six runs against Atlanta on April 15, the offense has failed to reach the five-run plateau in 11 straight games and only hit the four-run mark twice.Bo Bichette has been a bright spot, hitting safely in six of his last seven games and recording multiple hits in three of his last four. Three of his five career hits off Giolito have gone for extra bases, including one home run.Red Sox vs. Blue Jays Betting OddsWednesday 4/30Money LineRun LineTotal RunsBoston Red Sox-118-1.5 +136O 9.5 -102Toronto Blue Jays-102+1.5 -162U 9.5 -118Red Sox vs. Blue Jays expert picks and game predictionEven with this being Lucas Giolito's first start since 2023, there's little reason to expect Toronto to generate enough offense to even the series. At a fair price on DraftKings Sportsbook, the better value lies with the Red Sox run-line at plus money, with Jarren Duran and his mates staring back at a bunch of bullpen arms.Red Sox vs. Blue Jays Prediction: Boston Wins 9-5