#3 Borussia Dortmund 4-1 Real Madrid (Champions League semi-final first leg, April 2013)
With a place in the Champions League final at Wembley Stadium at stake, the two head coaches met again at the Signal Iduna Park in the semi-finals and Mourinho was once again made to taste defeat.
Ronaldo scored again at the Westfalenstadion in the first half after Robert Lewandowski had given BVB an early lead. The Polish frontman blew away the visitors in a 15-minute period in the second half as he went on to score three goals leaving the Madrid defence bruised and battered.
Video Courtesy: Memorable Match
This was Real's third consecutive Champions League semi-final appearance under Jose Mourinho and having lost the previous two, this 4-1 loss left his team on the brink of another semi-final exit.
This was the Portuguese's biggest defeat in 106 Champions League games. After the annihilation, a very frustrated Mourinho was clearly unhappy with his players as he said, "When we know everything, absolutely everything about Lewandowski -- we studied every detail possible and we lose him in three balls -- and we know exactly what he does, and it is of course very disappointing."
