5 major teams in danger of missing out on qualifying for the 2022 FIFA World Cup

#3 Wales

Wales v Estonia - 2022 FIFA World Cup Qualifier

Wales are currently third in Group E of the European World Cup Qualifiers with 11 points from six games. They are tied on points with second-placed Czech Republic but have an inferior goal difference. But Ryan Giggs' men do have a game in hand over Czech Republic.

But here's where it gets tricky. Czech Republic's final group game of the Qualifiers is against Estonia. Meanwhile, Wales will face Belarus on Saturday but their final game is against Belgium.

Suffice to say, Wales will have to play out of their skin to even make the playoffs as things stand. This could very well be Aaron Ramsey and Gareth Bale's final chance of playing in a World Cup. But the same old story of being utterly poor when it comes to qualifying for the World Cup looks set to repeat for the Welshmen.

#2 Switzerland and Italy

Italy v Switzerland - 2022 FIFA World Cup Qualifier

Italy's chances of qualifying for the World Cup received a major body check as they settled for a 1-1 draw against Switzerland on Friday. Jorginho missed a penalty as the Azzurri squandered the chance to put some daylight between themselves and second-placed Switzerland.

Italy and Switzerland are currently tied on points. Both sides have 15 points after seven matches but Italy's goal difference is +11 while Switzerland's is +9. Roberto Mancini's men will square off against the Republic of Ireland in their final game while Switzerland play Bulgaria.

Switzerland had an impressive run at Euro 2020. They eliminated tournament favourites France in the Round of 16 before falling to Spain in the penalty shootout in the quarter-finals.

#1 Uruguay

Uruguay v Argentina - FIFA World Cup Qatar 2022 Qualifier

Uruguay are South American footballing giants. Four teams will qualify from South America for the 2022 FIFA World Cup. Brazil and Argentina are both in great form and their qualifying campaigns are well on course. The remaining two spots are currently occupied by Ecuador and Chile.

Uruguay, who have lost the last three and are winless in their last four World Cup Qualifiers are languishing at sixth in the table. They have the same number of points as fourth-placed Chile but have a slightly inferior goal difference. Chile's GD is +1 while Uruguay's GD is -4.

Colombia are currently at fifth with a goal differece of -1. However, Uruguay have a relatively easier set of fixtures coming up as they're done with both rounds of games against Argentina and Brazil.

Chile have games against Argentina and Brazil. Colombia's games against the Selecao are over but they will face La Albiceleste once more. Uruguay still have a chance but they cannot afford to slip up anymore.

It would be rather unfortunate if Uruguay do end up missing out on a berth as this could be the last World Cup for Luis Suarez and Edinson Cavani.