#3 Uruguay vs Brazil (FIFA World Cup Qualifier)
The FIFA World Cup qualifiers always seem to have an intriguing aura around them, particularly in South America. Brazil have managed to fulfil their burgeoning potential in recent months but will now come up against a well-drilled and formidable Uruguay outfit.
The return of Jose Gimenez and Manchester United striker Edinson Cavani will serve as a massive boost for Oscar Tabarez's side. Benfica striker and Barcelona target Darwin Nunez has also been called up to his national team after an exceptional start to the season with the Portuguese giants.
Brazil have plenty of attacking talent of their own but with Philippe Coutinho nursing an injury, the onus will be on a recently-recovered Neymar to pull the strings for Selecao. The Paris Saint-Germain winger is yet to resume training and will hope that he can return in time for this all-important clash.
#2 Spain vs Germany (UEFA Nations League)
Spain and Germany have been two of the most successful European teams in world football in the recent past and have a point to prove going into this UEFA Nations League fixture. Both sides are in a phase of transition at the moment and have able tacticians in Joachim Low and Luis Enrique to guide them through a tricky patch.
Spain snatched a draw from the jaws of defeat in the previous meeting between these two sides last month as Jose Gaya restored parity for Luis Enrique's outfit with the last kick of the game. With prodigious forward Ansu Fati injured, the former Barcelona manager has made a few changes to his squad and will want to pick up a crucial victory in this game.
Germany need to consolidate their standing in the UEFA Nations League table and could potentially move to the top of their group with a victory in this game. Spain have the same end to achieve and will have to be at their best against Joachim Low's new-look side.
#1 Portugal vs France (UEFA Nations League)
Portugal are the only team that make two entries on this list and for good reason. In France, Fernando Santos will be up against one of the most settled line-ups in international football and will have to bank on his young stalwarts to deliver against the reigning World Champions.
France might not be the incredible force they were in the 2018 World Cup but still boast one of the best squads in Europe. The French team is littered with an immense array of talent and Portugal will have to be wary of the like of Kylian Mbappe and Antoine Griezmann.
Cristiano Ronaldo picked up a niggle against Lazio and remains doubtful for this fixture. With their talisman potentially unavailable, Portugal need to put in a complete performance to take something away from this game.