#1 Lazio

Lazio lost their star players Keita Balde to Monaco and Lucas Biglia to AC Milan. Despite that, they have gotten off to a good start domestically and in Europe. They won their European games against Vitesse and Zulte comfortably this season and are looking certain for a place in the knockout round.
Ciro Immobile has been the star so far with 9 goals and 3 assists this season well supported by Luis Alberto and Marco Parolo with 2 goals and 2 assists each.
They played against Arsenal two times in 2000/01 Champions League and could not come out top on both occasions. Lazio have been in and out of Europe in the recent past and lack the experience of AC Milan or Zenit. But they certainly has the ammunition to create an upset if Arsenal get lethargic.