Ajax and Groningen will trade tackles at the Johan Cruyff Arena on Saturday, with three points on the line in the Eredivisie.The home side come into the game on the back of a convincing 5-0 away victory over Fortuna Sittard on Wednesday. Five different men got on the scoresheet for the defending champions in the rout.Groningen suffered a 1-0 defeat to Vitesse on home turf on the same day. Yann Gboho scored the match-winner in first-half injury time in a game that saw the hosts finish the game with nine men.AFC Ajax@AFCAjaxThe boys are ready to play! 🎮#FIFA229:59 AM · Sep 23, 202126415The boys are ready to play! 🎮#FIFA22Ajax's victory meant they maintained their standing at the summit of the standings, with 16 points garnered from six matches. Groningen sit just two places outside the relegation zone and have accrued five points from six games.Ajax vs Groningen Head-to-HeadAjax have 35 wins from their last 48 matches against Groningen. The two sides shared the spoils on six occasions while the visitors were victorious in seven games.Their most recent meeting came in a league fixture in March when Ryan Gravenberch, Sebastian Haller and Dusan Tadic all got on the scoresheet in a 3-1 home victory for Ajax.The hosts are currently on a five-game winning run in all competitions, while Groningen have gone five games without a win.Ajax form guide (all competitions): W-W-W-W-WGroningen form guide: L-L-D-L-DAjax vs Groningen Team NewsAjax Davy Klaassen and Sean Klaiber have been sidelined with groin and knee injuries respectively. Goalkeeper Maarten Stekelenburg is a doubt with a groin injury while Andre Onana is still serving his suspension for failing a doping test.Injuries: Davy Klaassen, Sean KlaiberDoubtful: Maarten StekelenburgSuspension: Andre OnanaGroningen Laros Duarte, Wessel Dammers, Daleho Irandust and Marin Sverko are doubts for the trip to the capital. Radinio Balker is a long-term absentee with a cruciate ligament injury. Mike te Wierik and Daniel van Kaam are both suspended for the red card they received against Vitesse.Injuries: Radinio BalkerSuspension: Mike te Wierik, Daniel van KaamDoubtful: Laros Duarte, Wessel Dammers, Daleho Irandust, Marin SverkoAjax vs Groningen Predicted XIAjax Predicted XI (4-3-3): Remko Pasveer (GK); Noussair Mazraoui, Per Schuurs, Lisandro Martinez, Daley Blind; Edson Alvarez, Ryan Gravenberch, Steven Berghuis; Antony, Dusan Tadic, Sebastien HallerAFC Ajax@AFCAjax𝟭𝟲 years & 𝟭𝟯𝟬 days. Our youngest debutant ever. 💎#OnThisDay in 2018, @RGravenberch made his debut!#ForTheFuture9:16 AM · Sep 23, 202176752𝟭𝟲 years & 𝟭𝟯𝟬 days. Our youngest debutant ever. 💎#OnThisDay in 2018, @RGravenberch made his debut!#ForTheFuture https://t.co/rSFqqLgkC1Groningen Predicted XI (5-4-1): Peter Leeuwenburgh (GK); Bart van Hintum, Neraysho Kasanwirjo, Yahya Kelley, Bjorn Meijer, Mo El Hankouri; Patrick Joosten, Tomas Suslov, Cyril Ngonge, Damil Dankerlui; Jorgen LarsenAjax vs Groningen PredictionAjax are overwhelming favorites and their winning run is unlikely to be halted barring an unlikely upset.Groningen have been out-of-sorts but are capable of upsetting the form book, as evidenced by their consecutive victories over Ajax last year. The visitors are one of the cagiest sides in the league and they might mitigate the damage caused by an otherwise rampant Ajax attack.Prediction: Ajax 2-0 Groningen