The capital club were the dominant team in the game, taking the lead through Felipe Anderson. Lautaro Martínez equalised for Inter in the 51st minute, but Lazio struck twice in the final 15 minutes to secure all three points.
Cremonese, meanwhile, also suffered a defeat in their previous outing, falling to a 2-1 loss at home to Torino on Saturday. Their return to the top-flight has not been ideal, having lost all three games.
Inter Milan vs Cremonese Head-to-Head
The two northern Italian rivals have locked horns 21 times across competitions, but this will be their first meeting since the turn of the century. As expected, Inter have a better record, leading 14-3 in wins, while four games have ended in draws. Interestingly, all three wins for La Cremo against Inter have come at the San Siro, with the last one coming in the 1991-92 Serie A campaign.
Inter Milan form guide (all competitions): L-W-W
Cremonese form guide (all competitions): L-L-L-W
Inter Milan vs Cremonese Team News
Henrikh Mkhitaryan will be a key absentee for the Nerazzurri, as he's struggling with a hamstring issue. The Armenian is not expected to be risked here, with the first Derby della Madonnina of the season taking place on Saturday. Meanwhile, Dalbert and Gabriel Brazao are long-term absentees with injury.
Injured: Henrikh Mkhitaryan, Dalbert, Gabriel Brazao
There are no reported absentees for the visitors ahead of their trip to Milan.
Inter Milan vs Cremonese Predicted XIs
Inter Milan (3-5-2): Samir Handanovic; Milan Skriniar, Stefan de Vrij, Alessandro Bastoni; Denzel Dumfries, Hakan Calhanoglu, Marcelo Brozovic, Nicolo Barella, Federico Dimarco; Lautaro Martinez, Romelu Lukaku
Cremonese (3-4-1-2): Ionut Radu; Emanuel Aiwu, Vlad Chiriches, Luka Lochoshvili; Paolo Ghiglione, Charles Pickel, Santiago Ascacibar, Emanuele Valeri; Cristian Buonaiuto; David Okereke, Cyriel Dessers
Inter Milan vs Cremonese Prediction
Inter will look to return to winning ways here, as they face two tough games in the next ten days. They will meet reigning Serie A champions and arch-rivals AC Milan on Saturday before taking on Bayern Munich in their UEFA Champions League opener next Wednesday.
Cremonese, meanwhile, have struggled ontheir return to the top-flight, scoring three goals in three league games and conceding six, with only last-placed Monza conceding more. Considering the same, Inter should coast to a comfortable win.
Prediction: Inter Milan 3-0 Cremonese