Inter Milan are set to play Empoli at San Siro on Wednesday in the Round of 16 of the Coppa Italia.Inter Milan come into this game on the back of a 0-0 draw against Gian Piero Gasperini's Atalanta in the league. Inter Milan boasted the lion's share of possession while Atalanta managed more shots on target, but both teams were unable to find the net.Empoli, on the other hand, drew 1-1 against Paolo Zanetti's Venezia in the league. A first-half goal from Polish midfielder Szymon Zurkowski for Empoli was cancelled out by a second-half goal from Nigerian forward David Okereke for Venezia.Inter Milan vs Empoli Head-to-HeadIn 10 head-to-head encounters between the two sides, Inter Milan hold the clear advantage, having won nine games and drawn the other one.The two clubs last faced each other last year in Serie A, with Inter Milan beating Empoli 2-0. Goals from Italian full-backs Danilo D'Ambrosio and Federico Dimarco ensured victory for Inter Milan. Empoli had young midfielder Samuele Ricci sent off in the second-half.Inter Milan form guide in Serie A: D-W-W-W-WEmpoli form guide in Serie A: D-L-D-L-DInter Milan vs Empoli Team NewsInter MilanInter Milan have no known injury issues and manager Simone Inzaghi is expected to have a fully fit squad at his disposal.Injured: NoneDoubtful: NoneSuspended: NoneEmpoliMeanwhile, Empoli manager Aurelio Andreazzoli will be unable to call upon the services of Swedish midfielder Nicolas Haas and left-back Fabiano Parisi, while there are doubts over the availability of winger Federico Di Francesco.Injured: Fabiano Parisi, Nicolas HaasDoubtful: Federico Di FrancescoSuspended: NoneInter Milan vs Empoli Predicted XIInter Milan Predicted XI (3-5-2): Samir Handanovic, Stefan de Vrij, Andrea Ranocchia, Federico Dimarco, Denzel Dumfries, Roberto Gagliardini, Stefano Sensi, Matias Vecino, Aleksandar Kolarov, Joaquin Correa, Lautaro MartinezInter 🏆🇮🇹@Inter_en🧤 | HANDA #ForzaInter #AtalantaInter3:38 AM · Jan 17, 20221316🧤 | HANDA 👏👏#ForzaInter #AtalantaInter https://t.co/UNOQ4pIIs8Empoli Predicted XI (4-3-1-2): Guglielmo Vicario, Petar Stojanovic, Ardian Ismajli, Lorenzo Tonelli, Riccardo Fiamozzi, Samuele Ricci, Liam Henderson, Filippo Bandinelli, Szymon Zurkowski, Patrick Cutrone, Andrea La MantiaInter Milan vs Empoli PredictionInter Milan are currently top of the league table, two points ahead of 2nd-placed AC Milan. They have enjoyed an excellent season under Simone Inzaghi's management, and a deep run in the Coppa Italia would be another major positive.UEFA Champions League@ChampionsLeague Inter celebrate their first Italian Super Cup triumph since 2010 Key man was ______#UCL3:25 AM · Jan 13, 20226381330⚫️🔵 Inter celebrate their first Italian Super Cup triumph since 2010 🎉🏆🔝 Key man was ______#UCL https://t.co/9l5l3xUc4mEmpoli, on the other hand, are 11th in the league. They have not been in good form recently, and will be the underdogs going against Inter Milan.Inter Milan for the win.Prediction: Inter Milan 2-0 Empoli