The Yellow Submarine are one of the only four sides in the competition to have a 100% record after three games, and another win on Thursday would all but send them into the knockout stages.
The reigning Israeli champions, meanwhile, are just behind them in the group with six points, though another loss in the upcoming clash might allow Sivasspor to close the gap on them.
Maccabi Tel Aviv and Sivasspor are scheduled to meet in the final group stage game.
Maccabi Tel Aviv vs Villarreal Head-To-Head
In just three meetings, both sides have claimed a win each. Maccabi beat the La Liga side in a surprise 1-0 away victory in 2017 before the latter exacted revenge earlier this month with a 4-0 drubbing.
The first competitive game between them, however, which came three years ago in Tel Aviv, ended goalless.
Maccabi Tel Aviv Form Guide (all competitions): W-D-L-W-W
Villarreal Form Guide (all competitions): W-W-W-W-D
Maccabi Tel Aviv vs Villarreal Team News
Maccabi will be without long-term absentee Uros Nikolic, besides whom manager Giorgos Donis doesn't have any fresh concerns. However, full-back Enric Saborit is on two yellow cards and runs the risk of suspension for matchday five if he gets booked again on Thursday.
Injured: Uros Nikolic and Tal Ben Haim
Villarreal have Dani Parejo, Juan Foyth, and Pervis Estupinan back in the squad, as the trio missed the first leg but featured in the league game to Real Madrid at the weekend. Alberto Moreno is the only long-term absentee.
Injured: Alberto Moreno
Maccabi Tel Aviv vs Villarreal Predicted XI
Maccabi Tel Aviv (5-4-1): Daniel Tenenbaum; Ben Bitton, Luis Hernandez, Eitan Tibi, Enric Saborit, Matan Baltaxa; Yonatan Cohen, Eden Karzev, Dan Glazer, Tal Ben Haim; Nick Blackman.
Villarreal (4-4-2): Sergio Asenjo; Mario Gasper, Raul Albiol, Pau Torres, Alfonso Pedraza; Miguel Trigueros, Vincent Iborra, Dani Parejo, Moi Gomez; Gerard Moreno, Carlos Bacca.
Maccabi Tel Aviv vs Villarreal Prediction
Villarreal had little trouble brushing aside Maccabi Tel Aviv in the first leg, and have been brilliant away from home this season, barring the 4-0 loss to Barcelona.
Unai Emery has done a great job since arriving at the club in the summer and his well-drilled unit look poised to eke out another victory in this encounter.
Prediction: Maccabi Tel Aviv 1-2 VillarrealPublished 24 Nov 2020, 20:59 IST