Middlesbrough are set to play hosts to Luton Town at the Riverside Stadium on Wednesday in their next EFL Championship fixture.Middlesbrough come into this game on the back of a 3-0 win over Millwall on Saturday at the Riverside Stadium. A brace from former Sunderland winger Duncan Watmore and a goal from young midfielder Marcus Tavernier ensured victory for Neil Warnock's Middlesbrough.Three goals, three points 👏 #UTB— Middlesbrough FC (@Boro) December 12, 2020Luton Town, on the other hand, beat Preston North End 3-0 on Saturday at Kenilworth Road. A hat-trick from Republic of Ireland international James Collins sealed the win for Nathan Jones' Luton Town.3️⃣ goals, 3️⃣ points 🔥Saturday’s don’t get much better 🧡#COYH | #allstandtogether pic.twitter.com/n90MgS4YNk— @LutonTown (@LutonTown) December 12, 2020Middlesbrough vs Luton Town Head-to-HeadIn two previous encounters between the two sides, Luton Town have won one game and drawn the other one.The two clubs last faced each other in February this year, with Luton Town beating Middlesbrough 1-0. A first-half goal from former Manchester United midfielder Ryan Tunnicliffe secured the win for Luton Town.Middlesbrough form guide in the EFL Championship: L-W-L-L-WLuton Town form guide in the EFL Championship: L-W-L-D-WMiddlesbrough vs Luton Town Team NewsMiddlesbrough manager Neil Warnock has a few players sidelined. Former Leeds United and Norwich City midfielder Jonny Howson, centre-back Grant Hall, striker Ashley Fletcher and centre-back Nathan Wood are all out injured. There are doubts over the availability of winger Marcus Browne.Injured: Ashley Fletcher, Grant Hall, Jonny Howson, Nathan WoodDoubtful: Marcus BrowneSuspended: NoneMeanwhile, Luton Town will be without Croatian goalkeeper Simon Sluga, striker Danny Hylton and midfielder Eunan O'Kane, who are all nursing injuries.Injured: Simon Sluga, Danny Hylton, Eunan O'KaneDoubtful: NoneSuspended: NoneMiddlesbrough vs Luton Town Predicted XIMiddlesbrough Predicted XI (4-4-2): Marcus Bettinelli, Anfernee Dijksteel, Dael Fry, Paddy McNair, Marc Bola, Marcus Tavernier, George Saville, Sam Morsy, Marvin Johnson, Duncan Watmore, Chuba AkpomLuton Town Predicted XI (4-3-3): James Shea, Matty Pearson, Tom Lockyer, Sonny Bradley, Dan Potts, Kiernan Dewsbury-Hall, Glen Rea, Pelly Ruddock Mpanzu, Harry Cornick, James Collins, George MoncurMiddlesbrough vs Luton Town PredictionMiddlesbrough sit ninth in the league table. New signing Duncan Watmore has done well so far, scoring four goals in six games, while former Arsenal attacker Chuba Akpom has had a slow start. The likes of Marcus Tavernier and Paddy McNair continue to be crucial for the side.Luton Town, on the other hand, have done well this season. They sit 11th in the league table, and under manager Nathan Jones they have performed above expectations. Veteran striker James Collins has been fundamental to these performances.A close match is expected, with Middlesbrough likely to emerge victorious.Prediction: Middlesbrough 2-1 Luton TownAlso Read: Paris Saint-Germain vs Lorient prediction, preview, team news and more | Ligue 1 2020-21