Manchester City and Manchester United locked horns at the Etihad Stadium in what went down as an entertaining game of football between the two great rivals. The game was expected to be tightly contested due to the history of the fixture, but the Cityzens showed their class with a 4-1 win to go six points clear at the top of the table. Cristiano Ronaldo's absence was the headline team news for the away side, with the Portuguese star reportedly missing out due to a hip problem. Edinson Cavani and Raphael Varane were also out, so Ralf Rangnick was forced to make a handful of changes to his squad.Kevin De Bruyne broke the deadlock in the Manchester derby with a close-range finish, with the Manchester United backline left in tatters in the opening moments of the game. The home side dominated proceedings and threatened to double their advantage, but Manchester United struck back through Jadon Sancho, who found the bottom corner from just outside the penalty area to restore parity. Manchester City grew in stature as the game progressed and restored their lead before half-time, as De Bruyne doubled his tally with another close-range finish after the ball ricocheted kindly towards him. Manchester United lose to arch-rivals in Cristiano Ronaldo's absenceThe second half showed the gulf of class between the two sides, as Manchester City took initiative of the game right from the get-go. Pep Guardiola's side dominated possession and added another goal through Riyad Mahrez, whose sweetly struck volley found its way into the back of the net via a slight deflection.Mahrez scored another late in the game to cap off what turned out to be a happy outing for the hosts, as the table-toppers made a massive statement with a commanding victory.On that note, here are some of the best tweets from a derby that turned out to be a one-sided affair at the Etihad Stadium. Adroit Cadet@Adroit_CadetMaguire is 29. There is no magical upward trajectory. His flaws will become more pronounced in the coming years. People like Chiellini, T.Silva & co. have always had incredible closing intensity, so they were destined to be ageless10:54 PM · Mar 6, 20222064447Maguire is 29. There is no magical upward trajectory. His flaws will become more pronounced in the coming years. People like Chiellini, T.Silva & co. have always had incredible closing intensity, so they were destined to be agelessJ7@lfcJ7_United going from Ferdinand to Maguire11:01 PM · Mar 6, 2022874United going from Ferdinand to Maguire https://t.co/646OJJSGbr-@AnfieldRd96They once compared Wan-Bissaka to Trent.I feel sick.11:10 PM · Mar 6, 202288163They once compared Wan-Bissaka to Trent.I feel sick.Yuwan@U1sidMaguire jeez what are you even good at11:23 PM · Mar 6, 20221Maguire jeez what are you even good atDaveOCKOP@DaveOCKOPPlease watch that goal again. Maguire, back to goal, let the ball go under his legs back into danger instead of just tapping it away for a corner.10:30 PM · Mar 6, 20223254530Please watch that goal again. Maguire, back to goal, let the ball go under his legs back into danger instead of just tapping it away for a corner.Ben Webb@BenWebbLFCCalling Harry Maguire a fridge is offensive to fridges….10:10 PM · Mar 6, 20221254153Calling Harry Maguire a fridge is offensive to fridges….R8 🚜🌾@NabyllionaireRemember when tried running Maguire and Lindelof being better than VVD and Matip when they had all those 3pm kickoffs nobody was watching 10:30 PM · Mar 6, 202237723Remember when tried running Maguire and Lindelof being better than VVD and Matip when they had all those 3pm kickoffs nobody was watching 😭😭😭😭😭Ryan. 🔰@Vintage_UtdJadon Sancho is the one, man.10:22 PM · Mar 6, 20226669314Jadon Sancho is the one, man.Sam@SamueILFCMight be overreacting a little bit, but Jadon Sancho is England’s best forward.10:23 PM · Mar 6, 202284926Might be overreacting a little bit, but Jadon Sancho is England’s best forward.C (Blue Moon)@AFC_CarysI know his goal and assist stats are nice, but Bruno must be so jarring to watch as a United fanThe way he ruined that chance for Sancho…10:52 PM · Mar 6, 202241831I know his goal and assist stats are nice, but Bruno must be so jarring to watch as a United fanThe way he ruined that chance for Sancho…UtdDistrict 🇺🇦@UtdDistrict🗣 Roy Keane on Sancho's goal: "Lovely. Absolutely beautiful." [Sky Sports]10:56 PM · Mar 6, 20222068121🗣 Roy Keane on Sancho's goal: "Lovely. Absolutely beautiful." [Sky Sports]Jude Bellingham@BellinghamJudeJS, big game player.🤷🏽‍♂️10:24 PM · Mar 6, 2022573854808JS, big game player.🤷🏽‍♂️Jordan@FourFourJordanI’m crying De Gea finally comes out and takes Wan-Bissaka’s shins with him.10:42 PM · Mar 6, 202237113I’m crying De Gea finally comes out and takes Wan-Bissaka’s shins with him.niran@TheOfficialFNGwan-bissaka plays football as if he's wearing sandals11:14 PM · Mar 6, 202280228wan-bissaka plays football as if he's wearing sandalsMaram AlBaharna@maramperninetyThe gap in quality from Shaw to Telles and Dalot to Wan-Bissaka is so obvious. Sometimes the only important analysis is looking at the personnel.10:54 PM · Mar 6, 202241053The gap in quality from Shaw to Telles and Dalot to Wan-Bissaka is so obvious. Sometimes the only important analysis is looking at the personnel.UtdArena@UtdArenaWan-Bissaka was incredible for that. The flick over the challenge and then the outlet lob. Pogba’s pass was excellently weighted and Sancho’s brilliance finished it off. He’s been an efficient scorer throughout his career and showed why.10:24 PM · Mar 6, 202274992Wan-Bissaka was incredible for that. The flick over the challenge and then the outlet lob. Pogba’s pass was excellently weighted and Sancho’s brilliance finished it off. He’s been an efficient scorer throughout his career and showed why.R8 🚜🌾@NabyllionairePogba don't be a thug when you lose the ball challenge10:12 PM · Mar 6, 20221332Pogba don't be a thug when you lose the ball challengeR8 🚜🌾@NabyllionairePogba stinking it up but getting goal contributions omds they're gonna do what they did in 201810:24 PM · Mar 6, 20221527Pogba stinking it up but getting goal contributions omds they're gonna do what they did in 2018Umir@umirf1That Pogba dispossession there, that very nearly lead to a Man City goal is an example of those innate individual flaws to his game. That's not a problem of system. It's him and it makes him too unreliable to be elite in the first or second phase in the league.10:43 PM · Mar 6, 202217314That Pogba dispossession there, that very nearly lead to a Man City goal is an example of those innate individual flaws to his game. That's not a problem of system. It's him and it makes him too unreliable to be elite in the first or second phase in the league..@disgame21Pogba retain the ball in ur own half in a t6 game challenge (impossible)10:18 PM · Mar 6, 20224315Pogba retain the ball in ur own half in a t6 game challenge (impossible)⛷@stokaljonaunlocking Pogba: season six10:13 PM · Mar 6, 202211028unlocking Pogba: season six https://t.co/M6W6T75MRPJohn Muller@johnspacemullerRude of De Bruyne to break the unwritten rule that if a defender points at you, you're marked.10:09 PM · Mar 6, 202261268Rude of De Bruyne to break the unwritten rule that if a defender points at you, you're marked. https://t.co/m55lcnktGt𝓛𝓮𝓮🍊@IeeSZNKEVIN DE BRUYNE OH MY GOD HE IS NOT FUCKING REAL10:28 PM · Mar 6, 202246717KEVIN DE BRUYNE OH MY GOD HE IS NOT FUCKING REALalex@lfcalexx6there are still people that think City are better without De Bruyne btw11:02 PM · Mar 6, 2022132there are still people that think City are better without De Bruyne btwTrey@UTDTreyMan I hate this De Bruyne guy10:28 PM · Mar 6, 20223318173Man I hate this De Bruyne guyMahbub@MK98_____Mahrez is that fella in a group project who will turn up when you've finished all the work and sign off his name on it10:48 PM · Mar 6, 20224620Mahrez is that fella in a group project who will turn up when you've finished all the work and sign off his name on itWilliam Hill@WilliamHillOnly two Premier League players have scored 20 goals across all competitions this season: Mohamed Salah Riyad Mahrez Respect Riyad. 11:32 PM · Mar 6, 20226124Only two Premier League players have scored 20 goals across all competitions this season:🇪🇬 Mohamed Salah🇩🇿 Riyad Mahrez 🆕Respect Riyad. ✊ https://t.co/Sre4cJeXcT.@dxnii50Starting Mahrez in a game is like starting with 10 men, brother only starts playing when they’re 3 or 4 up10:27 PM · Mar 6, 2022485Starting Mahrez in a game is like starting with 10 men, brother only starts playing when they’re 3 or 4 upA🤾🏽‍♂️@AkzyyDead serious I didn’t even know Mahrez was playing until now10:34 PM · Mar 6, 20223739Dead serious I didn’t even know Mahrez was playing until now𝓛𝓮𝓮🍊@IeeSZNRIYAD MAHREZ THE ALGERIAN KINGGGG 11:28 PM · Mar 6, 202224513RIYAD MAHREZ THE ALGERIAN KINGGGG 🇩🇿🇩🇿🇩🇿🇩🇿🇩🇿Jaz@J7zzaSancho equalled CHO's league tally in 60 less games10:24 PM · Mar 6, 202236550Sancho equalled CHO's league tally in 60 less games😭😭