Just 3 points separate Ralf Rangnick's side from Wolfsburg in the Bundesliga points table, so the Die Bullen can ill afford a slip-up within their pursuit to qualify to the Champions League next season. Leipzig are in a rich vein of form and have not tasted defeat in their last 5 matches. Their league form is much better with the Die Bullen having won 3 of their last 4 matches.
Hoffenheim too will be looking for getting back into the European competitions with Julian Nagelsmann side just 8 points behind their opponents. The focus of the match though will be on their manager Julian Naglesmann, who will be managing Hoffenheim in the league for the last time before taking over the job at the Red Bull Arena at the end of the 2018-19 season. Hoffenheim will be targeting for another win after the side remained unbeaten in their last 4 matches.
The first encounter between the sides ended with Leipzig winning 2-1 at the PreZero Arena in Hoffenheim.
RB Leipzig will be certainly without Dayot Upamecano, as the defender is still recovering from a knee injury while Amadou Haidara and Emile Smith Rowe are doubtful for the fixture.
Ermin Bičakčić, Benjamin Hübner, and Lukas Rupp remain a major concern for Nagelsmann with the three of them doubtful for this fixture.
RB Leipzig (4-4-2): Gulacsi, Klostermann, Orban, Konate, Halstenberg; Sabitzer, Adams, Demme, Forsberg; Werner, Poulsen
Hoffenheim (3-4-1-2): Baumann, Adams, Vogt, Posch; Kaderabek, Geiger, Demirbay, Schulz; Kramaric; Belfodil, Joelinton