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#3 Marcos Llorente (Atletico Madrid)
Diego Simeone's reinvention of Marcos Llorente from defensive midfielder to centre-forward to all-action attacking midfielder is nothing short of miraculous. If anything, Zinedine Zidane may be casting a jealous eye on his former charge, with Llorente perhaps better than the options he currently has.
The €30 million that Atletico Madrid paid for his services looks ever more like a bargain every day. There ought to be plenty of regrets at Real Madrid - only Karim Benzema has outscored Llorente this season from their entire squad.
Real Madrid have looked vulnerable on the counter this season, with all of Casemiro, Toni Kroos and Luka Modric failing to track midfield runners - an area Marcos Llorente excels at.
Having lost to his boyhood club twice in three games, Llorente will be keen to score against Zinedine Zidane's side and aid Atletico Madrid in their quest for a victory.
#2 Sergio Ramos (Real Madrid)
The numbers 92:48 ought to be enough for any Rojiblanco fan to shiver at the thought of Sergio Ramos, but he looms larger than that moment in Lisbon. The centre-back has only lost 9 out of 44 games against Atletico Madrid, a stellar record in the Madrid derby.
Six goals and three assists make the Rojiblancos his favourite opponents, with Barcelona and Sevilla in second place. Clearly, Ramos is one for the big games.
His absence this season has been keenly felt, no less than by Raphael Varane, who's looked half the player without his Spanish partner.
Ramos' return came at the perfect moment for Zidane, with a great performance to shut out Borussia Monchengladbach.
Ramos faces quite the test against this version of a free-scoring Atletico, having kept a clean sheet in the last three games against them.
Joao Felix and Luis Suarez will be sure to test Ramos to the limit of his capabilities as he marshals a defence that looks lost without him.
#1 Luis Suarez (Atletico Madrid)
Luis Suarez knows the worth of a goal against Real Madrid, having been involved in 16 of them (11G, 5A) in his 15 appearances for Barcelona. Statistically, Real Madrid are the Uruguayan forwards' third favourite opponents, behind Valencia and Sevilla.
It's the perfect occasion to see his Atletico career take off, especially with Suarez having scored just three goals in ten games following his brace against Granada on debut.
Suarez looked the picture of frustration having been substituted against Salzburg, with Diego Simeone accepting his forward's reaction.
An angry Suarez is a goalscoring Suarez if his career is anything to go by, so Real Madrid ought to be quite wary.
Sergio Ramos and Raphael Varane know exactly how annoying an opponent he can be, and with Joao Felix profiting from Suarez's hard yards, he is a sure bet to have an impact on this Madrid derby.
