Real Madrid host Osasuna at the Alfredo Di Stéfano Stadium in La Liga on Saturday, looking to return to winning ways.The reigning Spanish champions were held to a goalless draw by Real Betis last weekend, their second such result in a week, losing ground in the title race.Although Los Blancos remain in second position in the La Liga table, two points off leaders Atletico Madrid, their arch-rivals Barcelona have a game in hand. A win for Barca in Thursday's game against Granada would propel them to the summit.With just five games remaining in the season, Zinedine Zidane's side cannot afford any more slip-ups. This is especially true as they have a more challenging home-stretch of the campaign compared to their top-three rivals.Meanwhile, the Rojillos have little to fight for as they remain 10 points clear of the bottom-three and are all but assured of retaining their top-flight status.However, the Pamplona outfit have caused problems for Real Madrid in the past and the holders cannot afford to underestimate their threat.Real Madrid vs Osasuna Head-To-HeadIn 35 previous clashes between the sides, Real Madrid have beaten Osasuna on 23 occasions, while losing only five times.However, their match in Pamplona earlier this season ended in a goalless stalemate.😃 Con la mejor de las actitudes para afrontar el reto del sábado.¡Vamos, equipo!🔜 #RealMadridOsasuna pic.twitter.com/IynK5lYna3— C. A. OSASUNA (@CAOsasuna) April 29, 2021Real Madrid Form Guide (all competitions): D-D-W-D-DOsasuna Form Guide (all competitions): D-W-W-W-LReal Madrid vs Osasuna Team NewsReal MadridThe embattled holders were dealt another major blow after Daniel Carvajal was ruled out for the rest of the season with a hamstring injury.That leaves Zidane in a spot of bother, with Ferland Mendy also doubtful for the clash. Nacho will need to be at left-back while Eder Militao is the likely option to fill in for Carvajal at right-back.Lucas Vazquez and Federico Valverde have long-term injuries.Injured: Daniel Carvajal, Lucas Vazquez, Federico Valverde, and Ferland MendySuspended: NoneUnavailable: NoneParte médico de Carvajal.#RealMadrid— Real Madrid C.F. (@realmadrid) April 29, 2021OsasunaGoalkeeper Ruben Martinez is recovering from a hand fracture. Los Rojillos will stick with Sergio Herrera in goal, while Inigo Perez is out with a muscle injury.Head coach Jagoba Arrasate might tinker with his formation a little after the loss to Celta Vigo, with Javi Martinez and Roberto Torres in line to start. Meanwhile, Chimy Avila is also in with a shout for a starting berth ahead of the erratic Ante Budimir.Injured: Ruben Martinez and Sergio HerreraSuspended: NoneUnavailable: NoneReal Madrid vs Osasuna Predicted XIReal Madrid (4-3-3): Thibaut Courtois; Eder Militao, Raphael Varane, Sergio Ramos, Nacho; Luka Modric, Casemiro, Toni Kroos; Vinicius Junior, Karim Benzema, Marco Asensio.Osasuna (4-5-1): Sergio Herrera; Facundo Roncaglia, Jonas Ramalho, Unai Garcia, Juan Cruz; Kike Barja, Darko Brasanac, Jon Moncayola, Roberto Torres, Ruben Garcia, Chimy Avila.Real Madrid vs Osasuna PredictionIt's no secret that Los Blancos have lost steam lately, but with a title defense on the line, expect them to turn up the heat in this game.Prediction: Real Madrid 2-0 Osasuna