A win for the French side will confirm a spot in the knockout round for them, while Vitesse need a win here to keep the pressure on Tottenham Hotspur for a second-place finish in Group G.
Rennes are one of the most in-form teams in Europe at the moment and are unbeaten in their last 11 games across all competitions. Their 4-1 win over Lyon in Ligue 1 proved this purple patch is no fluke and they should not be taken lightly by their competitors.
Rennes vs Vitesse Head-to-Head
The reverse fixture at GelreDome in October was the first meeting between the two sides. The game ended in a 2-1 away win for the hosts, who scored twice in the second half to complete a comeback against the Dutch side.
Rennes form guide (all competitions): W-W-W-D-W
Vitesse form guide (all competitions): L-W-L-W-L
Rennes vs Vitesse Team News
Jeremy Gelin is the only player who will miss the game on account of an injury. He has been ruled out with an ACL injury and is expected back in the fold in March.
Injured: Jeremy Gelin
Eric Verstappen is ineligible to play in European competition while Daan Reiziger has been ruled out for the remainder of the campaign with a wrist injury.
Oussama Darfalou is missing due to fitness issues, while Hilary Gong has withdrawn from the squad as he has just become a father and is with his family for the next week.
Captain Danilho Doekhi and goalkeeper Markus Schubert are suspended for the game following their red cards in the 3-2 loss at Tottenham Hotspur last week.
Injured: Daan Reiziger, Oussama Darfalou
Suspended: Danilo Doekhi, Markus Schubert
Unavailable: Eric Verstappen, Hilary Gong
Rennes vs Vitesse Predicted XI
Rennes Predicted XI (4-3-3): Alfred Gomis; Adrien Truffert, Nayef Aguerd, Warmed Omari, Hamari Traore; Flavien Tait, Jonas Martin, Kamaldeen Sulemana; Jérémy Doku, Martin Terrier, Gaetan Laborde
Vitesse Predicted XI (3-4-2-1): Jeroen Houwen; Tomas Hajek, Jacob Rasmussen, Bazoer; Maximilian Wittek, Yann Gboho, Sondre Tornstad, Eli Dasa; Thomas Buitink, Lois Openda; Nikolai Baden Frederiksen
Rennes vs Vitesse Prediction
Vitesse won't be able to field their strongest starting XI here and that might cause some trouble against an in-form Rennes. Les Rennais are in good touch and also have an almost full-strength squad to count on.
When the two sides go head-to-head on Thursday, the game is expected to end in a comfortable win for the Ligue 1 side.
ALSO READArticle Continues below
Prediction: Rennes 2-0 Vitesse