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Best NFL DFS Picks for Sunday: Dolphins vs. 49ers - December 4 | 2022 NFL Regular Season

Houston Texans v Miami Dolphins
Can Tua Tagovailoa lead the Miami Dolphins to a road victory over the San Francisco 49ers?

The Miami Dolphins head out west to take on the San Francisco 49ers. What a game this could be!

Both teams are surging at the right time and are in the lead of their current divisions.

Will Miami continue to lead the AFC East, or will the 49ers' continue their dominance of the NFC West?

Best quarterback picks

Cash Games: Tua Tagovailoa, QB, Miami Dolphins (DraftKings $6.7K, FanDuel $7.8K)

If Miami is to win this game, Tua Tagovailoa will have to play great.

Tournaments: Jimmy Garoppolo, QB, San Francisco 49ers (Draftkings $5.7K, FanDuel $7K)

Jimmy Garoppolo is the cheaper option of the two QBs in this game and carries less ownership. This situation sounds like a tournament play to me.

Best running back picks

Cash Games: Christian McCaffrey, RB, San Francisco 49ers (DraftKings $8.6K, FanDuel $8.2K)

This week is a game where I could see the 49ers lean on Christian McCaffrey more than they have in recent weeks. Do the 49ers want to go throw-for-throw with Miami? I believe they would prefer to grind it out by running the football.

Tournament: Jeff Wilson Jr., RB, Miami Dolphins (DraftKings $6.1K, FanDuel $6.8K)

With Raheem Mostert healthy, Jeff Wilson Jr. won't have to handle every-down duties for the Dolphins, but he should retain the majority share of the backfield work. Can the Dolphins' offensive line find some success against the 49ers' stellar front seven?

Wide receivers and tight ends

Cash Games: Tyreek Hill, WR, Miami Dolphins (DraftKings $8.8K, FanDuel $9K)

Tyreek Hill has been great all season long. The difference that 'The Cheetah' has made for the Dolphins' offense and QB Tua Tagovailoa cannot be understated.

Hill has been phenomenal against man-and-zone coverage, so there appears to be no answer for him, given the way the Dolphins utilize him in their offense. Even against a tough match-up, it is hard to get away from Tyreek Hill in Cash games.

Tournament: Deebo Samuel, WR, San Francisco 49ers (DraftKings $6.6K, FanDuel $6.8K)

Deebo Samuel has been inconsistent lately for the San Francisco 49ers, and there are several reasons for that. For starters, we knew that the acquisition of Christian McCaffrey would negatively impact Deebo Samuel.

Samuel is utilized in the underneath areas as a pass-catcher and runner. Sound like someone you know? Christian McCaffrey works in those areas as well. With Christian McCaffrey, Deebo Samuel, George Kittle, and Brandon Aiyuk, there are a lot of mouths to feed in San Francisco.

The good news is that recent developments have caused Samuels' price tag to drop significantly to the point that he is a screaming value at his current price. In a match-up with the Dolphins, which could shoot out, Deebo is a tournament play.

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Edited by Mudeet Arora